Phorbol-diester hydrolase

Phorbol-diester hydrolase

In enzymology, a phorbol-diester hydrolase (EC number|3.1.1.51) is an enzyme that catalyzes the chemical reaction

:phorbol 12,13-dibutanoate + H2O ightleftharpoons phorbol 13-butanoate + butanoate

Thus, the two substrates of this enzyme are phorbol 12,13-dibutanoate and H2O, whereas its two products are phorbol 13-butanoate and butanoate.

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is 12,13-diacylphorbate 12-acylhydrolase. Other names in common use include diacylphorbate 12-hydrolase, diacylphorbate 12-hydrolase, phorbol-12,13-diester 12-ester hydrolase, and PDEH.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|81181-74-0."

Gene Ontology (GO) codes


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