RNA ligase (ATP)

RNA ligase (ATP)

In enzymology, a RNA ligase (ATP) (EC number|6.5.1.3) is an enzyme that catalyzes the chemical reaction

:ATP + (ribonucleotide)n + (ribonucleotide)m ightleftharpoons AMP + diphosphate + (ribonucleotide)n+m

The 3 substrates of this enzyme are ATP, (ribonucleotide)n, and (ribonucleotide)m, whereas its 3 products are AMP, diphosphate, and (ribonucleotide)n+m.

This enzyme belongs to the family of ligases, specifically those forming phosphoric-ester bonds. The systematic name of this enzyme class is poly(ribonucleotide):poly(ribonucleotide) ligase (AMP-forming). Other names in common use include polyribonucleotide synthase (ATP), RNA ligase, polyribonucleotide ligase, and ribonucleic ligase.

tructural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes PDB link|1VDX and PDB link|2C5U.

References

*

External links

::"The CAS registry number for this enzyme class is CAS registry|37353-39-2."

Gene Ontology (GO) codes


Wikimedia Foundation. 2010.

Игры ⚽ Нужно сделать НИР?

Look at other dictionaries:

  • RNA-3'-phosphate cyclase — In enzymology, a RNA 3 phosphate cyclase (EC number|6.5.1.4) is an enzyme that catalyzes the chemical reaction:ATP + RNA 3 terminal phosphate ightleftharpoons AMP + diphosphate + RNA terminal 2 ,3 cyclic phosphateThus, the two substrates of this… …   Wikipedia

  • ligase — /luy gays, gayz/, n. Biochem. any of a class of enzymes that catalyze the joining of two molecules by formation of a covalent bond accompanied by the hydrolysis of ATP. [1961; < L lig(are) to tie, bind + ASE] * * * ▪ biochemistry also called… …   Universalium

  • ATP-dependent DNA helicase 2 subunit 2 — X ray repair complementing defective repair in Chinese hamster cells 5 (double strand break rejoining; Ku autoantigen, 80kDa), also known as XRCC5, is a human gene. PBB Summary section title = summary text = The protein encoded by this gene is… …   Wikipedia

  • Alanine-tRNA ligase — In enzymology, an alanine tRNA ligase (EC number|6.1.1.7) is an enzyme that catalyzes the chemical reaction:ATP + L alanine + tRNAAla ightleftharpoons AMP + diphosphate + L alanyl tRNAAlaThe 3 substrates of this enzyme are ATP, L alanine, and… …   Wikipedia

  • Phenylalanine-tRNA ligase — In enzymology, a phenylalanine tRNA ligase (EC number|6.1.1.20) is an enzyme that catalyzes the chemical reaction:ATP + L phenylalanine + tRNAPhe ightleftharpoons AMP + diphosphate + L phenylalanyl tRNAPheThe 3 substrates of this enzyme are ATP,… …   Wikipedia

  • Isoleucine-tRNA ligase — In enzymology, an isoleucine tRNA ligase (EC number|6.1.1.5) is an enzyme that catalyzes the chemical reaction:ATP + L isoleucine + tRNAIle ightleftharpoons AMP + diphosphate + L isoleucyl tRNAIleThe 3 substrates of this enzyme are ATP, L… …   Wikipedia

  • Lysine-tRNA ligase — In enzymology, a lysine tRNA ligase (EC number|6.1.1.6) is an enzyme that catalyzes the chemical reaction:ATP + L lysine + tRNALys ightleftharpoons AMP + diphosphate + L lysyl tRNALysThe 3 substrates of this enzyme are ATP, L lysine, and… …   Wikipedia

  • DNA ligase — repairing chromosomal damage Identifiers EC number 6.5.1.1 …   Wikipedia

  • Asparagine-tRNA ligase — In enzymology, an asparagine tRNA ligase (EC number|6.1.1.22) is an enzyme that catalyzes the chemical reaction:ATP + L asparagine + tRNAAsn ightleftharpoons AMP + diphosphate + L asparaginyl tRNAAsnThe 3 substrates of this enzyme are ATP, L… …   Wikipedia

  • Tyrosine-tRNA ligase — In enzymology, a tyrosine tRNA ligase (EC number|6.1.1.1) is an enzyme that catalyzes the chemical reaction:ATP + L tyrosine + RNA ightleftharpoons AMP + triphosphate + L tyrosyl tRNATyrThe 3 substrates of this enzyme are ATP, L tyrosine, and RNA …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”