- Maleylacetate reductase
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maleylacetate reductase Identifiers EC number 1.3.1.32 CAS number 69669-65-4 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a maleylacetate reductase (EC 1.3.1.32) is an enzyme that catalyzes the chemical reaction
- 3-oxoadipate + NAD(P)+
2-maleylacetate + NAD(P)H + H+
The 3 substrates of this enzyme are 3-oxoadipate, NAD+, and NADP+, whereas its 4 products are 2-maleylacetate, NADH, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-oxoadipate:NAD(P)+ oxidoreductase. This enzyme is also called maleolylacetate reductase. This enzyme participates in 3 metabolic pathways: gamma-hexachlorocyclohexane degradation, benzoate degradation via hydroxylation, and 1,4-dichlorobenzene degradation.
References
- Gaal AB, Neujahr HY (1980). "Maleylacetate reductase from Trichosporon cutaneum". Biochem. J. 185 (3): 783–6. PMC 1161460. PMID 7387635. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1161460.
- Gaal AB and Neujahr HY (1981). "Induction of phenol-metabolizing enzymes in Trichosporon cutaneum". Arch. Microbiol. 130 (1): 54–58. doi:10.1007/BF00527072. PMID 7305599.
This EC 1.3 enzyme-related article is a stub. You can help Wikipedia by expanding it. - 3-oxoadipate + NAD(P)+
