- (+)-neomenthol dehydrogenase
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(+)-neomenthol dehydrogenase Identifiers EC number 1.1.1.208 CAS number 81811-47-4 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a (+)-neomenthol dehydrogenase (EC 1.1.1.208) is an enzyme that catalyzes the chemical reaction
- (+)-neomenthol + NADP+
(-)-menthone + NADPH + H+
Thus, the two substrates of this enzyme are (+)-neomenthol and NADP+, whereas its 3 products are (-)-menthone, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (+)-neomenthol:NADP+ oxidoreductase. This enzyme is also called monoterpenoid dehydrogenase. This enzyme participates in monoterpenoid biosynthesis.
References
- Kjonaas R, Martinkus-Taylor C and Croteau R (1982). "Metabolism of monoterpenes: conversion of l-menthone to l-menthol and d-neomenthol by stereospecific dehydrogenases from peppermint (Mentha piperita) leaves". Plant Physiol. 69 (5): 1013–1017. doi:10.1104/pp.69.5.1013. PMC 426349. PMID 16662335. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=426349.
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