Honey Bee Genome Sequencing Consortium

Honey Bee Genome Sequencing Consortium

The Honey Bee Genome Sequencing Consortium is an international collaborative group of genomics scientists, scientific organisations and universities who are trying to decipher the genome sequences of the honey bee ("Apis mellifera"). It was formed in 2001 by American scientists. In the US, the project is funded by the National Human Genome Research Institute (a division of the National Institutes of Health (NIH)), the United States Department of Agriculture (USDA), the Texas Agricultural Experiment Station, the University of Illinois Sociogenomics Initiative, and various beekeepers association and the bee industry.

First scientific findings show that the honey bee genome may have evolved more slowly than the genomes of the fruit fly and malaria mosquito. [ Robinson, Gene and Weaver, Daniel, The Honey Bee Genome Project: A Model of Cooperation between Academia, Government, and Industry; American Bee Journal Oct. 2006 pg. 870ff] The bee genome contains versions of some important mammalian genes.

The complete genome of "Apis mellifera" has been sequenced and consists of 10,000 genes with approximately 236 million base pairs. The genome is ten times smaller than the human genome [Weinstock et al., [http://www.nature.com/nature/journal/v443/n7114/full/nature05260.html;jsessionid=557ACDE1D76290DFE51E4E312D0D8A67 Insights into social insects from the genome of the honeybee Apis mellifera] Nature 443, 931-949, 2006] . The Western honey bee gene sequence showed 163 chemical receptors for smell but only 10 for taste. Besides the discovery of new genes for the use of pollen and nectar, researchers found that, in comparison with other insects, "Apis mellifera" has fewer genes for immunity, detoxification and the development of the cuticula [Robertson, Hugh M. and Wanner, Kevin W. [http://www.genome.org/cgi/content/full/16/11/1395 The chemoreceptor superfamily in the honey bee, Apis mellifera: Expansion of the odorant, but not gustatory, receptor family ] Genome Research, Volume 16, Page 1395, 2006] .The population genetic analysis showed Africa as the origin and hypothesized that the spread into Europe happened in at least two independent waves. [Whitfield, Charles W. et al.: [http://www.sciencemag.org/cgi/content/abstract/314/5799/642 Thrice Out of Africa: Ancient and Recent Expansions of the Honey Bee, Apis mellifera.] Science, Vol. 314. no. 5799, pp. 642 - 645, 2006]

Data from the scientific collaboration is made available on Beebase led by Texas A&M University. [ [http://racerx00.tamu.edu/bee_resources.html BeeBase] ]

BeeSpace led by the University of Illinois [ [http://www.beespace.uiuc.edu/ BeeSpace] ] is an effort to complete a web navigable catalog of related information.

ee also

*List of sequenced eukaryotic genomes

ources


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