Human foamy virus

Human foamy virus

Taxobox
name = "PAGENAME"
virus_group = vi
familia = "Retroviridae"
subfamilia = "Spumaretrovirinae"
genus = "Spumavirus"
species = "Simian foamy virus"
subdivision_ranks = Serotype
subdivision = "Human foamy virus"

Human foamy virus (HFV) is a VI spumavirus virus also known as spumaretrovirus. It is a member of the Retroviridae family and for this reason has two positive sense RNA genomes. This means that this virus is a true diploid. The virus was first identified in 1971 from lymphoblastoid cells within a Kenya patient with nasopharyngeal carcinoma (above the soft palate of pharynx of the nasal passage). The isolation and sequencing of a chimpanzee foamy virus isolate made clear, that human foamy virus is a variant of that widespread simian foamy virus, hence, not no authentic infectious agent present in human populations.

Genome

The viral genome of this retrovirus is complex, as it contains not only the "gag", "pol" and "env" genes, but also genes that encode proteins that are not incorporated into the viral particle. These are termed "bel-1" ("tas") and "bet". The function for "bet" is still unclear; however, it is known that the "tas" gene is a transactivator that plays a role in viral replication.

The way in which the virus replicates also differs from that of most retroviruses, as it may leave the cells via exocytosis using vesicles from the endoplasmic reticulum where some reverse transcription of the virus has taken place. Also, when reverse transcription happens late in viral replication, some particles produced contain DNA instead of RNA.

ymptoms

Humans are an accidental host for the virus (most people only become infected when exposed to it within the laboratory or from a monkey bite), so there are no known symptoms of this disease. To date, no human-to-human transmission has been documented.

External links

*


Wikimedia Foundation. 2010.

Игры ⚽ Нужно решить контрольную?

Look at other dictionaries:

  • Human foamy virus —   Human foamy virus Clasificación de los virus Grupo: VI (Viru …   Wikipedia Español

  • Simian foamy virus — Taxobox name = PAGENAME virus group = vi familia = Retroviridae subfamilia = Spumaretrovirinae genus = Spumavirus species = Simian foamy virus The simian foamy virus (SFV) is a spumavirus closely related to HIV, the virus that causes AIDS. Its… …   Wikipedia

  • Virus — A microorganism smaller than a bacteria, which cannot grow or reproduce apart from a living cell. A virus invades living cells and uses their chemical machinery to keep itself alive and to replicate itself. It may reproduce with fidelity or with… …   Medical dictionary

  • Mouse mammary tumor virus — Virus classification Group: Group VI (ssRNA RT) Family: Retroviridae Subfamily: Orthoretrovirina …   Wikipedia

  • Simian immunodeficiency virus — Virus classification Group: Group VI (ssRNA RT) Family: Retroviridae Genus: Lentivirus …   Wikipedia

  • Visna virus — Virus classification Group: Group VI (ssRNA RT) Family: Retroviridae Subfamily: Orthoretrovirinae …   Wikipedia

  • Murine leukemia virus — MMLV redirects here. It is also the Roman numeral for 2055. Murine leukemia virus Virus classification Group: Group VI (ssRNA RT) Family: Retroviridae Subfamily …   Wikipedia

  • DsDNA-RT virus — DsDNA RT viruses are the seventh group in the Baltimore virus classification. They are not considered as DNA viruses (class I of Baltimore classification), but rather reverse transcribing viruses because they replicate through an RNA intermediate …   Wikipedia

  • Feline immunodeficiency virus — Taxobox name = Feline immunodeficiency virus virus group = vi familia = Retroviridae subfamilia = Orthoretrovirinae genus = Lentivirus species = Feline immunodeficiency virus Feline immunodeficiency virus (FIV), occasionally referred to as Feline …   Wikipedia

  • Liste De Virus — Ceci est une liste de virus biologiques et de types de virus. Veuillez ajouter ou modifier cette liste si nécessaire. Certains de ces termes peuvent être des synonymes pour le même virus ; s il existe déjà un article sur ce virus sous un… …   Wikipédia en Français

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”