Guido Fanconi

Guido Fanconi

Guido Fanconi (1 January1892 – 10 October 1979) was a Swiss pediatrician. He was born in Poschiavo, Canton Grisons (Graubünden) in the Italian-speaking region of Switzerland. Fanconi is regarded as one of the founders of modern pediatrics.

He received his secondary school education in the German-speaking part of Switzerland. In 1911, he began his medical training in Lausanne (French Switzerland). In 1920, he entered the Kinderspital (Children's Hospital) of the University of Zurich, where, with the exception of one year, he remained for 45 years.

Fanconi recognized the importance of biochemistry to clinical medicine. In 1929 he succeeded Emil Feer as professor of pediatrics and head of the Kinderspital. Under his direction, it became one of the most renowned children's hospitals in the world.

There are several medical conditions named after Dr. Fanconi. In 1927 he described hereditary panmyelopathy with short stature and hyperpigmentation, better known as Fanconi anemia. In 1934 the first cases of cystic fibrosis of the pancreas were described in a thesis written under his direction. In 1941 a large epidemic of poliomyelitis occurred in Switzerland. Fanconi analyzed its epidemiology and found that the virus was not transmitted by droplet infection, as previously assumed, but rather follows a gastrointestinal pathway like typhoid fever. His understanding of pathophysiologic connections culminated in his prediction that Down syndrome was due to a chromosomal abnormality, 20 years before trisomy 21 was discovered.

In 1945 he founded a new pediatric journal, "Helvetica Paediatrica Acta", which has become an internationally renowned periodical. Dr. Fanconi retired in 1965 from his chairmanship in pediatrics, but continued to practice and lecture until his death.

ee also

* Fanconi anemia
* Prader-Willi syndrome, discovered by a team of physicians including Fanconi.
* Fanconi syndrome, likely a misnomer, as this entity was not described by Fanconi.

References

* Journal of Pediatrics. 96(4), pg. 674

External links

* [http://www.whonamedit.com/doctor.cfm/40.html Who Named It? - Guido Fanconi]
* [http://www.nature.com/nrc/journal/v6/n11/pdf/nrc2009.pdf Biography of Guido Fanconi] by Stephan Lobitz (Berlin, Germany) and Eunike Velleuer (Düsseldorf, Germany), published in "Nature Reviews Cancer" (Nov. 2006)


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  • Guido Fanconi — est un pédiatre suisse né à Poschiavo (canton des Grisons en Suisse, région de langue italienne le 1er janvier 1892, décédé à Poschiavo le 10 octobre 1979. Dipl …   Wikipédia en Français

  • Guido Fanconi — Guido Fanconi, ca. 1959 Guido Fanconi (* 1. Januar 1892 in Poschiavo (Graubünden); † 10. Oktober 1979 ebenda) war ein Schweizer Kinderarzt. Er beschrieb im Jahre 1927 erstmals die nach ihm benannte Fanconi Anämie, eine extrem seltene und oft… …   Deutsch Wikipedia

  • Guido Fanconi — Guido Fanconi, ca. 1938 Guido Fanconi ( * 1 de enero 1892 – 10 de octubre 1979) fue un pediatra suizo …   Wikipedia Español

  • Fanconi — Guido Fanconi, ca. 1959 Guido Fanconi (* 1. Januar 1892 in Poschiavo (Graubünden); † 10. Oktober 1979 ebenda) war ein Schweizer Kinderarzt. Er beschrieb im Jahre 1927 erstmals die nach ihm benannte Fanconi Anämie, eine extrem seltene und oft… …   Deutsch Wikipedia

  • Fanconi anemia — DiseaseDisorder infobox Name = Fanconi Anemia ICD10 = ICD10|D|61|0|d|60 ICD9 = ICD9|284.0 ICDO = Caption = OMIM = 227650 OMIM mult = MedlinePlus = 000334 eMedicineSubj = ped eMedicineTopic = 3022 DiseasesDB = 4745 MeshID = D005199 Fanconi anemia… …   Wikipedia

  • Fanconi syndrome — Not to be confused with Fanconi anemia. Fanconi syndrome Classification and external resources ICD 10 E72.0 ICD 9 …   Wikipedia

  • Fanconi-Anämie — Klassifikation nach ICD 10 D61.0 Angeborene aplastische Anämie Fanconi Anämie …   Deutsch Wikipedia

  • Fanconi anemia — A genetic (inherited) disease that adversely affects all of the bone marrow elements and is closely associated with malformations of the heart, kidney and limbs (arms and legs) as well as pigmentary changes of the skin. Fanconi anemia predisposes …   Medical dictionary

  • Fanconi pancytopenia — A genetic (inherited) disease that adversely affects all of the bone marrow elements and is closely associated with malformations of the heart, kidney and limbs (arms and legs) as well as pigmentary changes of the skin. Fanconi pancytopenia,… …   Medical dictionary

  • Fanconi's anaemia — noun a rare congenital anemia characterized by pancytopenia and hypoplasia of the bone marrow • Syn: ↑Fanconi s anemia, ↑congenital pancytopenia • Hypernyms: ↑anemia, ↑anaemia, ↑genetic disease, ↑genetic disorder, ↑ …   Useful english dictionary

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