Pyrazole

Pyrazole

Chembox new
ImageFileL1=Pyrazole_numbering.pngImageSizeL1=100px
ImageFileR1=Pyrazole3d.pngImageSizeR1=100px
IUPACName=Pyrazole
OtherNames=1,2-diazole
Section1= Chembox Identifiers
CASNo=288-13-1
PubChem=
ChemSpiderID = 1019
SMILES=C1=CC=NN1

Section2= Chembox Properties
Formula=C3H4N2
MolarMass=68.07 g/mol
Appearance=
Density=
MeltingPt=66-70 °C
BoilingPt=168-188 °C
Solubility=
pKa =
pKb =

Section3= Chembox Hazards
MainHazards=
FlashPt=
Autoignition=

Section8 = Chembox Related
OtherCpds =

Pyrazole refers both to the class of simple aromatic ring organic compounds of the heterocyclic series characterized by a 5-membered ring structure composed of three carbon atoms and two nitrogen atoms in adjacent positions and to the unsubstituted parent compound. Being so composed and having pharmacological effects on humans, they are classified as alkaloids, although they are rare in nature.

Pyrazoles

Pyrazoles are produced synthetically through the reaction of α,β-unsaturated aldehydes with hydrazine and subsequent dehydrogenation.

In medicine, pyrazoles are used for their analgesic, anti-inflammatory, antipyretic, antiarrhythmic, tranquilizing, muscle relaxing, psychoanaleptic, anticonvulsant, monoamineoxidase inhibiting, antidiabetic and antibacterial activities.

Pyrazoles react with potassium borohydride to form a class of ligands known as Scorpionates.

Structurally related compounds are pyrazoline and pyrazolidine.

See also

* Benzimidazole, an imidazole analog with a fused benzene ring.
* Pyrrole, an analog with only one nitrogen atom in position 1.
* Oxazole, an analog with the nitrogen atom in position 1 replaced by oxygen.
* Imidazole, an analog with two non-adjacent nitrogen atoms.
* Simple aromatic rings
* Phenylbutazone,Pyrazolone, pyrazolidinedione, 4-butyl-1,2-diphenyl-pyrazolidine-3,5-dione.


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  • Pyrazole —      Général …   Wikipédia en Français

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  • pyrazole — /pir euh zohl , zawl /, n. Chem. 1. any of the group of heterocyclic compounds containing three carbon atoms, two adjacent nitrogen atoms, and two double bonds in the ring. 2. the parent compound, C3H4N2. [1885 90; PYR + AZOLE] * * * ▪ chemical… …   Universalium

  • Pyrazole — Pyrazol Pyrazole sind eine Stoffgruppe heterocyclischer chemischer Verbindungen. Sie besitzen einen fünfgliedrigen Ring mit zwei benachbarten Stickstoffatomen und gehörten zu den Heteroaromaten, genauer zu den Azolen. Sie sind isomer zu den… …   Deutsch Wikipedia

  • pyrazole — pyr·azole pir ə .zōl n 1) a crystalline heterocyclic weakly basic compound C3H4N2 isomeric with imidazole 2) any of various derivatives of pyrazole …   Medical dictionary

  • pyrazole — pirazolas statusas T sritis chemija apibrėžtis Penkianaris heterociklinis junginys. formulė C₃H₄N₂ atitikmenys: angl. pyrazole rus. пиразол …   Chemijos terminų aiškinamasis žodynas

  • pyrazole — ˈpirəˌzōl, zȯl noun Etymology: International Scientific Vocabulary pyr + azole; originally formed as German pyrazol 1. : a crystalline feeble heterocyclic base C3H4N2 isomeric with imidazole obtained usually by action of acetylene on… …   Useful english dictionary

  • pyrazole — noun a) A heterocyclic organic compound containing two nitrogen atoms next to each others in a five membered ring, called 1,2 diazole in . b) A group of compounds containing that structure …   Wiktionary

  • pyrazole — pyr·azole …   English syllables

  • pyrazole — /ˈpɪrəzɒl/ (say piruhzol) noun 1. a colourless crystalline solid, C3H4N2, serving as the parent substance of important dyestuffs. 2. Chemistry any of a group of monocyclic organic compounds containing two adjacent nitrogen atoms in a five… …  

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