NovaMin

Calcium sodium phosphosilicate
Properties
Molecular formula	CaNaO6PSi
Molar mass	218.123431
Y (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

NovaMin is the brand name of a particulate bioactive glass that is used in dental care products for Remineralisation of teeth. It was developed and patented by NovaMin Technology, Inc.. The active ingredient is the inorganic chemical calcium sodium phosphosilicate.^[1]

NovaMin delivers silica and ionic calcium, phosphorus, and sodium, which are necessary for bone and tooth mineralization.

How it works

NovaMin particles bind to the tooth surface and, when the particle comes in contact with saliva and water, react with the water to release calcium and phosphate ions. These ions are protected by glass particles so that they can be delivered to specific locations rather than as a liquid solution. Sodium ions in the particles exchange with hydrogen cations, which allows the calcium and phosphate ions to be released. A calcium phosphate layer then forms and crystallizes as hydroxyapatite, a form of hard and strong mineral in teeth. The physical occlusion of dentinal tubules results from both the hydroxyapatite layer and the residual Novamin particles.^[1][2]

The chemical reaction that leads to hydroxyapatite is:

5Ca²⁺ + 3PO₄^3– + OH^– → Ca₅(PO₄)₃(OH)

Uses

• Treating dentine hypersensitivity ^[3]
• Promoting remineralisation of teeth ^[4]

Products Containing NovaMin

• OSspray Sylc Therapeutic Prophy Powder [4] (US & EU)
• OSspray Sylc SmarTip Prophy System [5] (US & EU)
• NUPRO Sensodyne Prophylaxis Paste with NovaMin, used in professional teeth cleaning by dentists and hygienists for cleaning, stain removal and sensitivity relief
• Sensodyne NUPRO Professional Toothpaste with NovaMin, dentist-dispensed toothpaste with 5,000 ppm Fluoride and NovaMin for use at home
• Sensodyne Repair & Protect
• Sultan Topex Renew Paste
• DenShield (EU/Asia)
• Dr. Collins Restore Toothpaste (US)
• Nanosensitive hca (EU)
• Oravive No longer available as of 30 April 2010
• SensiShield (EU)
• SootheRx (US/CDN) No longer available as of 30 June 2011
• Burt's Bees Natural Toothpaste (US)
• SHY-NM, (India)
• Vantej , (India)
• Odontis-Rx (Brazil)
• X-Pur Tooth Revitalizing Paste (Canada)

Although some products are sold only through dentists, other products are available in stores or via Internet sales.

Acquisition of Novamin by GSK

Novamin were acquired by GlaxoSmithKline in May 2010 for $135 million. ^[5]

See also

• Fluoride
• Recaldent

References

1. ^ ^{a b} http://www.gcamerica.com/images/pdfs/recaldent_comparison.pdf Comparison of RECALDENT
2. ^ Anti-gingivitis effect of a dentifrice containing bioactive glass (NovaMin) particulate [1]
3. ^ A Randomized Parallel Group Clinical Study Evaluating the Efficacy of Three Desensitizing Dentifrices [2]
4. ^ Evaluation of NovaMin as an Adjunct to Fluoride For Caries Lesion Remineralization [3]
5. ^ http://www.gainesville.com/article/20100523/ARTICLES/5231002/1002

External links

• NovaMin Technology, Inc's website

This dentistry article is a stub. You can help Wikipedia by expanding it.v · Categories: Dental materials Dentistry stubs Wikimedia Foundation. 2010. Игры ⚽ Поможем написать реферат Agriculture in Portugal Jefisley André Caldeira Look at other dictionaries: Novamin — Strukturformel Allgemeines Freiname Metamizol Andere Namen Dipyrone Novaminsulfo …   Deutsch Wikipedia Fluoride therapy — is the delivery of fluoride to the teeth topically or systemically in order to prevent tooth decay (dental caries) which results in cavities. Most commonly, fluoride is applied topically to the teeth using gels, varnishes, toothpaste/dentifrices… …   Wikipedia Bioactive glass — Bioactive glasses are a group of surface reactive glass ceramics and include the original bioactive glass, Bioglass. The biocompatibility of these glasses has led them to be investigated extensively for use as implant materials in the human body… …   Wikipedia Dentine hypersensitivity — is sensation felt when the nerves inside the dentin of the teeth are exposed to the environment. The sensation can range from irritation all the way to intense, shooting pain. This sensitivity can be caused by several factors, including wear,… …   Wikipedia Remineralisation of teeth — is a process in which minerals are returned to the molecular structure of the tooth itself. This process cannot replace lost tooth material (that is, it will not fill a cavity that has developed into a hole)… …   Wikipedia МЕТЕРАЗИН — ( Metherazinum ). 2 Хлор 10 [3 (1 метилпиперазинил 4) пропил] фенотиазина дималеат. Синонимы: Chlormeprazine, Chlorperazin, Compazine, Dicopal, Nipodal, Novamin, Prochlorpemazine, Prochlorperazini maleas, Prochlorperazine maleate, Stemetil,… …   Словарь медицинских препаратов Metherazinum — МЕТЕРАЗИН ( Metherazinum ). 2 Хлор 10 [3 (1 метилпиперазинил 4) пропил] фенотиазина дималеат. Синонимы: Chlormeprazine, Chlorperazin, Compazine, Dicopal, Nipodal, Novamin, Prochlorpemazine, Prochlorperazini maleas, Prochlorperazine maleate,… …   Словарь медицинских препаратов Прохлорперазин — Химическое соединение ИЮПАК  ? Брутто формула  ? Классификация АТХ …   Википедия Метеразин — Прохлорперазин (Prochlorperazinum). 2 Хлор 10 [3 Синонимы: Chlormeprazine, Chlorperazin, Meterazine, Compazine, Dicopal, Nipodal, Novamin, Prochlorpemazine, Prochlorperazini maleas, Prochlorperazine maleate, Stemetil, Temetil и др. Содержание 1… …   Википедия 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”