SCH-530348

Drugbox
IUPAC_name = Ethyl "N"- [(3"R",3a"S",4"S",4a"R",7"R",8a"R",9a"R")-4- [("E")-2- [5-(3-fluorophenyl)-2-pyridyl] vinyl] -3-methyl-1-oxo-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3"H"-benzo [f] isobenzofuran-7-yl] carbamate

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CAS_number = 618385-01-6
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PubChem = 10077130
DrugBank =
C=29|H=33|F=1|N=2|O=4
molecular_weight = 492.58 g/mol
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SCH-530348 is a thrombin receptor (PAR-1) antagonists based on the natural product himbacine. Developed by Schering-Plough, SCH-530348 is a potential treatment for acute coronary syndrome chest pain caused by coronary artery disease.cite journal|author= Samuel Chackalamannil|title=Discovery of a Novel, Orally Active Himbacine-Based Thrombin Receptor Antagonist (SCH 530348) with Potent Antiplatelet Activity|journal=Journal of Medicinal Chemistry|year=2008|doi =10.1021/jm800180e|volume= 51|pages= 3061]

References

External links

* [http://pubs.acs.org/email/cen/html/021806150931.html C&EN]
* [http://www.chemspider.com/8252668 ChemSpider Article]