- Ointment
An ointment is a viscous semisolid preparation used topically on a variety of body surfaces. These include the
skin and themucus membrane s of theeye (an "eye ointment"),vagina ,anus , andnose . An ointment may or may not be medicated.Description
The vehicle of an ointment is known as ointment base. The choice of a base depends upon the clinical indication for the ointment, and the different types of ointment bases are:
#Hydrocarbon bases. e.g. hard paraffin, soft paraffin.
#Absorption bases. e.g. wool fat, beewax.
#Water soluble bases. e.g. macrogols 200,300,400.Properties which affect choice of an ointment base are:
#Stability
#Penetrability
#Solvent property
#Irritant effects
#Ease of application and removalMethods of preparation of ointments
Trituration: In this finely subdivided insoluble medicaments are evenly distributed by grinding with a small amount of the base followed by dilution with gradually increasing amounts of the base.
Fusion: In this method the ingredients are melted together in descending order of their melting points and stirred to ensure homogenity
Topical medication forms
(Source: [Doctor, why are you prescribing an ointment?;American Academy of Dermatology;http://www.skincarephysicians.com/eczemanet/doctor.html] )
* Cream - Emulsion of oil and water in approximately equal proportions. Penetrates
stratum corneum outer layer of skin well.*
Ointment - Combines oil (80%) and water (20%). Effective barrier against moisture loss.*
Gel - Liquefies upon contact with the skin.* Paste - Combines three agents - oil, water, and powder; an ointment in which a powder is suspended.
* Powder
ee also
*
Cream (pharmaceutical)
*Lotion
*Liniment
*Gel External links
* [http://www.rpsgb.org.uk/pdfs/mussheet06.pdf History of ointments]
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