5,10-Methenyltetrahydrofolate
- 5,10-Methenyltetrahydrofolate
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Section1= Chembox Identifiers
CASNo=7444-29-3
PubChem=644350
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MeSHName=5,10-methenyltetrahydrofolate
Section2= Chembox Properties
Formula=C20H213N7O6
MolarMass=455.42 g/mol
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5,10-Methenyltetrahydrofolate (5,10-CH=THF) is a form of tetrahydrofolate that is an intermediate in metabolism. 5,10-CH=THF is a coenzyme that accepts and donates methenyl (CH=) groups.
It is produced from 5,10-methylenetetrahydrofolate by either a NAD+ dependent methylenetetrahydrofolate dehydrogenase, or a NADP+ dependent dehydrogense. [cite journal |author=Fowler B |title=The folate cycle and disease in humans |journal=Kidney Int. Suppl. |volume=78 |pages=S221–9 |year=2001 |month=February |pmid=11169015] It can also be produced as an intermediate in histidine catabolism, by formiminotransferase cyclodeaminase, from 5-formiminotetrahydrofolate.
5,10-CH=THF is a substrate for methenyltetrahydrofolate cyclohydrolase, which converts it into 10-formyltetrahydrofolate.
References
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Look at other dictionaries:
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Cyclodeaminase domain — FTCD C crystal structure of formiminotetrahydrofolate cyclodeaminase (tm1560) from thermotoga maritima at 2.80 a resolution Identifiers Symbol FTCD C … Wikipedia
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Acide 5,10-méthényltétrahydrofolique — Structure de l acide 5,10 méthényltétrahydrofolique Général No CAS … Wikipédia en Français
