FightAIDS@Home

__NOTOC__ FightAIDS@Home ("Fight AIDS at home") is a distributed computing project for internet-connected home computers, operated by the "Olson Laboratory" at The Scripps Research Institute. It aims to use biomedical software simulation techniques to search for ways to cure or prevent the spread of AIDS and HIV.

It was originally implemented using a distributed computing software infrastructure provided by Entropia. However, since May 2003 FightAIDS@Home has not been associated with Entropia, [cite web
url=http://www.futurepundit.com/archives/001822.html
title=Worthy Cause: Fight AIDS At Home Computer Project
publisher=FuturePundit
date=2003-12-01
accessdate=2007-08-08] and on November 21, 2005 the project moved to World Community Grid and the Entropia software was abandoned. [cite web
url=http://fightaidsathome.scripps.edu/
title=FightAIDS@Home
publisher=The Scripps Research Institute
accessdate=2007-08-08]

FightAIDS@Home makes use of the AutoDock UD agent software, which tests how well a particular molecule binds to the HIV-1 protease. The minimum system requirements to run FightAIDS@home are: [cite web
url=http://www.worldcommunitygrid.org/help/viewTopic.do?shortName=minimumreq
title=System Requirements
publisher=World Community Grid
work=Help
accessdate=2007-08-08]

Scripps Research Institute published its first peer-reviewed scientific paper about the results of FightAIDS@Home on April 21, 2007. [cite web
url=http://pubs.acs.org/cgi-bin/sample.cgi/jcisd8/2007/47/i03/html/ci700044s.html
title=Analysis of HIV Wild-Type and Mutant Structures via in Silico Docking against Diverse Ligand Libraries
work=J. Chem. Inf. Model
publisher=American Chemical Society
author=Chang, Max W.
coauthors=William Lindstrom, Arthur J. Olson, and Richard K. Belew
date=2007-04-21
accessdate=2007-07-30
doi=10.1021/ci700044s] This paper explains that the results up to that point will primarily be used to improve the efficiency of future FightAIDS@Home calculations. [cite web
url=http://fightaidsathome.scripps.edu/news/vol3.pdf
title=FightAIDS@Home News Volume 3
publisher=The Scripps Research Institute
date=2007-05-10
accessdate=2007-07-30]

Publications

Citation
last = Chang
first = Max W.
author-link =
last2 = Lindstrom
first2 = William
author2-link =
last3 = Olson
first3 = Arthur J.
author3-link =
last4 = Belew
first4 = Richard K.
author4-link =
title = Analysis of HIV Wild-Type and Mutant Structures via in Silico Docking against Diverse Ligand Libraries
journal = J. Chem. Inf. Model.
volume = 47
issue = 3
pages = 1258 - 1262
date =
year = 2007
url = http://pubs.acs.org/cgi-bin/sample.cgi/jcisd8/2007/47/i03/pdf/ci700044s.pdf
doi = 10.1021/ci700044s
id =

See also

* List of distributed computing projects

References

External links

* [http://www.worldcommunitygrid.org/projects_showcase/viewFaahResearch.do World Community Grid - Research - FightAIDS@Home]
* [http://fightaidsathome.scripps.edu/ FightAIDS@Home] at Scripps
* [http://www.scripps.edu/news/press/112105.html World Community Grid Targets AIDS in Giant Research Effort]