Aldicarb

Chembox new
Name = Aldicarb
ImageFile = Aldicarb-2D-skeletal.png ImageName = Skeletal formula of aldicarb
ImageFile1 = Aldicarb-3D-balls.png ImageName1 = Ball-and-stick model of aldicarb
IUPACName = 2-methyl-2-(methylthio)propionaldehyde O-methylcarbamoyloxime
Section1 = Chembox Identifiers
CASNo = 116-06-3
Section2 = Chembox Properties
Formula = C₇H₁₄N₂O₂S
MolarMass = 190.27 g/mol
Density = 1.195 g/cm³
MeltingPt = 100 °C
BoilingPt = Decomposes before boiling point

Aldicarb is a carbamate insecticide with structural formula: 2-methyl-2-(methylthio)propionaldehyde O-methylcarbamoyloxime. Aldicarb is the active substance in Temik pesticide, which is effective against thrips, aphids, spider mites, lygus, fleahoppers, and leafminers but is primarily used as a nematicide. [cite web
publisher = [http://www.bayercropscienceus.com/ Bayer CropScience]
url = http://www.bayercropscienceus.com/products_and_seeds/insecticides/temik.html
title = Temik
accessdate = 2008-01-11 ] Aldicarb is a cholinesterase inhibitor which prevents the breakdown of acetylcholine in the synapse. In case of severe poisoning, the victim dies of respiratory failure.

Regulatory Status

Aldicarb is approved by the USEPA for use by professional pesticide applicators on a variety of crops, including cotton, beans, and others. It is not approved for household use. [cite web
date = June 1996
publisher = [http://extoxnet.orst.edu/ The Extension Toxicology Network]
work = Pesticide Information Profiles
url = http://extoxnet.orst.edu/pips/aldicarb.htm
title = Aldicarb
accessdate = 2007-08-13 ]

"Tres Pasitos", a mouse, rat, and roach killer that contains high concentrations of aldicarb, has been illegally imported into the United States from Mexico and other Latin American countries. The product is highly toxic to animals and people, and it should not be used. [http://www.epa.gov/pesticides/health/illegalproducts/#pet EPA]

Toxicity in mammals

Aldicarb is a fast-acting cholinesterase inhibitor, causing rapid accumulation of acetylcholine at the synaptic cleft.It is widely used to study cholinergic neurotransmission in simple systems such as the nematode "C. elegans".

Exposure to high amounts of aldicarb can cause weakness, blurred vision, headache, nausea, tearing, sweating, and tremors in people. Very high doses can kill people, because it can paralyze the respiratory system. [http://www.epa.gov/pesticides/health/illegalproducts/#pet EPA]

It has a LD50 rating of 0.5 - 1.5 mg/kg when in liquid form and a LD50 rating of 7mg/kg when in solid form.

ee also

*Pesticide toxicity to bees

References