- WFIKKN1
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1, also known as WFIKKN1, is a human
gene .cite web | title = Entrez Gene: WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=117166| accessdate = ]PBB_Summary
section_title =
summary_text = This gene encodes a secreted multidomain protein consisting of a signal peptide, a WAP domain, a follistatin domain, an immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. These domains have been implicated frequently in inhibition of various types of proteases, suggesting that the encoded protein may be a multivalent protease inhibitor and may control the action of multiple types of serine proteases as well as metalloproteinases.cite web | title = Entrez Gene: WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=117166| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Liepinsh E, Nagy A, Trexler M, "et al." |title=Second Kunitz-type protease inhibitor domain of the human WFIKKN1 protein. |journal=J. Biomol. NMR |volume=35 |issue= 1 |pages= 73-8 |year= 2006 |pmid= 16791741 |doi= 10.1007/s10858-006-9013-1
*cite journal | author=Brandenberger R, Wei H, Zhang S, "et al." |title=Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. |journal=Nat. Biotechnol. |volume=22 |issue= 6 |pages= 707-16 |year= 2005 |pmid= 15146197 |doi= 10.1038/nbt971
*cite journal | author=Nagy A, Trexler M, Patthy L |title=Expression, purification and characterization of the second Kunitz-type protease inhibitor domain of the human WFIKKN protein. |journal=Eur. J. Biochem. |volume=270 |issue= 9 |pages= 2101-7 |year= 2003 |pmid= 12709070 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Trexler M, Bányai L, Patthy L |title=Distinct expression pattern of two related human proteins containing multiple types of protease-inhibitory modules. |journal=Biol. Chem. |volume=383 |issue= 1 |pages= 223-8 |year= 2003 |pmid= 11928817 |doi=
*cite journal | author=Trexler M, Bányai L, Patthy L |title=A human protein containing multiple types of protease-inhibitory modules. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 7 |pages= 3705-9 |year= 2001 |pmid= 11274388 |doi= 10.1073/pnas.061028398
*cite journal | author=Daniels RJ, Peden JF, Lloyd C, "et al." |title=Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. |journal=Hum. Mol. Genet. |volume=10 |issue= 4 |pages= 339-52 |year= 2001 |pmid= 11157797 |doi=PBB_Controls
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