LASS1

LAG1 homolog, ceramide synthase 1 (S. cerevisiae), also known as LASS1, is a human gene.cite web | title = Entrez Gene: LASS1 LAG1 homolog, ceramide synthase 1 (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10715| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. Members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in yeast suggest that the encoded protein is involved in aging. This protein is transcribed from a monocistronic mRNA as well as a bicistronic mRNA, which also encodes growth differentiation factor 1.cite web | title = Entrez Gene: LASS1 LAG1 homolog, ceramide synthase 1 (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10715| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Koybasi S, Senkal CE, Sundararaj K, "et al." |title=Defects in cell growth regulation by C18:0-ceramide and longevity assurance gene 1 in human head and neck squamous cell carcinomas. |journal=J. Biol. Chem. |volume=279 |issue= 43 |pages= 44311-9 |year= 2004 |pmid= 15317812 |doi= 10.1074/jbc.M406920200
*cite journal | author=Grimwood J, Gordon LA, Olsen A, "et al." |title=The DNA sequence and biology of human chromosome 19. |journal=Nature |volume=428 |issue= 6982 |pages= 529-35 |year= 2004 |pmid= 15057824 |doi= 10.1038/nature02399
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Venkataraman K, Riebeling C, Bodennec J, "et al." |title=Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells. |journal=J. Biol. Chem. |volume=277 |issue= 38 |pages= 35642-9 |year= 2002 |pmid= 12105227 |doi= 10.1074/jbc.M205211200
*cite journal | author=Jiang JC, Kirchman PA, Zagulski M, "et al." |title=Homologs of the yeast longevity gene LAG1 in Caenorhabditis elegans and human. |journal=Genome Res. |volume=8 |issue= 12 |pages= 1259-72 |year= 1999 |pmid= 9872981 |doi=
*cite journal | author=Lee SJ |title=Expression of growth/differentiation factor 1 in the nervous system: conservation of a bicistronic structure. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=88 |issue= 10 |pages= 4250-4 |year= 1991 |pmid= 2034669 |doi=

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