- TESK2
Testis-specific kinase 2, also known as TESK2, is a human
gene .cite web | title = Entrez Gene: TESK2 testis-specific kinase 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10420| accessdate = ]PBB_Summary
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summary_text = This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain that is structurally similar to the kinase domains of testis-specific protein kinase-1 and the LIM motif-containing protein kinases (LIMKs). Its overall structure is most related to the former, indicating that it belongs to the TESK subgroup of the LIMK/TESK family of protein kinases. This gene is predominantly expressed in testis and prostate. The developmental expression pattern of the rat gene in testis suggests an important role for this gene in meitoic stages and/or early stages of spermiogenesis.cite web | title = Entrez Gene: TESK2 testis-specific kinase 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10420| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55-65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Toshima JY, Toshima J, Watanabe T, Mizuno K |title=Binding of 14-3-3beta regulates the kinase activity and subcellular localization of testicular protein kinase 1. |journal=J. Biol. Chem. |volume=276 |issue= 46 |pages= 43471-81 |year= 2001 |pmid= 11555644 |doi= 10.1074/jbc.M104620200
*cite journal | author=Toshima J, Toshima JY, Takeuchi K, "et al." |title=Cofilin phosphorylation and actin reorganization activities of testicular protein kinase 2 and its predominant expression in testicular Sertoli cells. |journal=J. Biol. Chem. |volume=276 |issue= 33 |pages= 31449-58 |year= 2001 |pmid= 11418599 |doi= 10.1074/jbc.M102988200
*cite journal | author=Røsok O, Pedeutour F, Ree AH, Aasheim HC |title=Identification and characterization of TESK2, a novel member of the LIMK/TESK family of protein kinases, predominantly expressed in testis. |journal=Genomics |volume=61 |issue= 1 |pages= 44-54 |year= 1999 |pmid= 10512679 |doi= 10.1006/geno.1999.5922PBB_Controls
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