LHX2

LHX2

LIM homeobox 2, also known as LHX2, is a human gene.cite web | title = Entrez Gene: LHX2 LIM homeobox 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9355| accessdate = ]

PBB_Summary
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summary_text = This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator. The protein can recapitulate or rescue phenotypes in Drosophila caused by a related protein, suggesting conservation of function during evolution.cite web | title = Entrez Gene: LHX2 LIM homeobox 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9355| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Glenn DJ, Maurer RA |title=MRG1 binds to the LIM domain of Lhx2 and may function as a coactivator to stimulate glycoprotein hormone alpha-subunit gene expression. |journal=J. Biol. Chem. |volume=274 |issue= 51 |pages= 36159-67 |year= 2000 |pmid= 10593900 |doi=
*cite journal | author=Bach I, Rodriguez-Esteban C, Carrière C, "et al." |title=RLIM inhibits functional activity of LIM homeodomain transcription factors via recruitment of the histone deacetylase complex. |journal=Nat. Genet. |volume=22 |issue= 4 |pages= 394-9 |year= 1999 |pmid= 10431247 |doi= 10.1038/11970
*cite journal | author=Rincón-Limas DE, Lu CH, Canal I, "et al." |title=Conservation of the expression and function of apterous orthologs in Drosophila and mammals. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 5 |pages= 2165-70 |year= 1999 |pmid= 10051612 |doi=
*cite journal | author=Bendall AJ, Rincón-Limas DE, Botas J, Abate-Shen C |title=Protein complex formation between Msx1 and Lhx2 homeoproteins is incompatible with DNA binding activity. |journal=Differentiation |volume=63 |issue= 3 |pages= 151-7 |year= 1998 |pmid= 9697309 |doi=
*cite journal | author=Wu HK, Heng HH, Siderovski DP, "et al." |title=Identification of a human LIM-Hox gene, hLH-2, aberrantly expressed in chronic myelogenous leukaemia and located on 9q33-34.1. |journal=Oncogene |volume=12 |issue= 6 |pages= 1205-12 |year= 1996 |pmid= 8649822 |doi=

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