- ARMET
Arginine-rich, mutated in early stage tumors, also known as ARMET, is a human
gene .cite web | title = Entrez Gene: ARMET arginine-rich, mutated in early stage tumors| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7873| accessdate = ]PBB_Summary
section_title =
summary_text = This gene encodes a highly conserved protein whose function is not yet known. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of a specific mutation changing the previously numbered codon 50 from ATG to AGG, or deletion of that codon, has been reported in a variety of solid tumors. With the protein size correction, this codon is now identified as the initiation codon.cite web | title = Entrez Gene: ARMET arginine-rich, mutated in early stage tumors| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7873| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Gevaert K, Goethals M, Martens L, "et al." |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566-9 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810
*cite journal | author=Lai MC, Kuo HW, Chang WC, Tarn WY |title=A novel splicing regulator shares a nuclear import pathway with SR proteins. |journal=EMBO J. |volume=22 |issue= 6 |pages= 1359-69 |year= 2003 |pmid= 12628928 |doi= 10.1093/emboj/cdg126
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Tanaka H, Shimada Y, Harada H, "et al." |title=Polymorphic variation of the ARP gene on 3p21 in Japanese esophageal cancer patients. |journal=Oncol. Rep. |volume=7 |issue= 3 |pages= 591-3 |year= 2000 |pmid= 10767373 |doi=
*cite journal | author=Shridhar V, Rivard S, Wang X, "et al." |title=Mutations in the arginine-rich protein gene (ARP) in pancreatic cancer. |journal=Oncogene |volume=14 |issue= 18 |pages= 2213-6 |year= 1997 |pmid= 9174057 |doi= 10.1038/sj.onc.1201054
*cite journal | author=Shridhar R, Shridhar V, Rivard S, "et al." |title=Mutations in the arginine-rich protein gene, in lung, breast, and prostate cancers, and in squamous cell carcinoma of the head and neck. |journal=Cancer Res. |volume=56 |issue= 24 |pages= 5576-8 |year= 1997 |pmid= 8971156 |doi=
*cite journal | author=Shridhar V, Rivard S, Shridhar R, "et al." |title=A gene from human chromosomal band 3p21.1 encodes a highly conserved arginine-rich protein and is mutated in renal cell carcinomas. |journal=Oncogene |volume=12 |issue= 9 |pages= 1931-9 |year= 1996 |pmid= 8649854 |doi=PBB_Controls
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