CENTD3

Centaurin, delta 3, also known as CENTD3, is a human gene.cite web | title = Entrez Gene: CENTD3 centaurin, delta 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64411| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a phosphoinositide binding protein containing ARF-GAP, RHO-GAP, RAS-associating, and pleckstrin homology domains. The ARF-GAP and RHO-GAP domains cooperate in mediating rearrangements in the cell cytoskeleton and cell shape. It is a specific PtdIns(3,4,5)P3/PtdIns(3,4)P2-stimulated Arf6-GAP protein. An alternatively spliced transcript has been found for this gene, but its full-length nature has not been determined.cite web | title = Entrez Gene: CENTD3 centaurin, delta 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64411| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Raaijmakers JH, Deneubourg L, Rehmann H, "et al." |title=The PI3K effector Arap3 interacts with the PI(3,4,5)P3 phosphatase SHIP2 in a SAM domain-dependent manner. |journal=Cell. Signal. |volume=19 |issue= 6 |pages= 1249-57 |year= 2007 |pmid= 17314030 |doi= 10.1016/j.cellsig.2006.12.015
*cite journal | author=Lu Q, Wei W, Kowalski PE, "et al." |title=EST-based genome-wide gene inactivation identifies ARAP3 as a host protein affecting cellular susceptibility to anthrax toxin. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 49 |pages= 17246-51 |year= 2005 |pmid= 15569923 |doi= 10.1073/pnas.0407794101
*cite journal | author=I ST, Nie Z, Stewart A, "et al." |title=ARAP3 is transiently tyrosine phosphorylated in cells attaching to fibronectin and inhibits cell spreading in a RhoGAP-dependent manner. |journal=J. Cell. Sci. |volume=117 |issue= Pt 25 |pages= 6071-84 |year= 2005 |pmid= 15546919 |doi= 10.1242/jcs.01526
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Reinhard C, Schweikert M, Wieland FT, Nickel W |title=Functional reconstitution of COPI coat assembly and disassembly using chemically defined components. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 14 |pages= 8253-7 |year= 2003 |pmid= 12832619 |doi= 10.1073/pnas.1432391100
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Santy LC, Casanova JE |title=GTPase signaling: bridging the GAP between ARF and Rho. |journal=Curr. Biol. |volume=12 |issue= 10 |pages= R360-2 |year= 2002 |pmid= 12015138 |doi=
*cite journal | author=Krugmann S, Anderson KE, Ridley SH, "et al." |title=Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices. |journal=Mol. Cell |volume=9 |issue= 1 |pages= 95-108 |year= 2002 |pmid= 11804589 |doi=

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