GBA2

Glucosidase, beta (bile acid) 2, also known as GBA2, is a human gene.cite web | title = Entrez Gene: GBA2 glucosidase, beta (bile acid) 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57704| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a microsomal beta-glucosidase that catalyzes the hydrolysis of bile acid 3-O-glucosides as endogenous compounds. Studies to determine subcellular localization of this protein in the liver indicated that the enzyme was mainly enriched in the microsomal fraction where it appeared to be confined to the endoplasmic reticulum. This putative transmembrane protein is thought to play a role in carbohydrate transport and metabolism.cite web | title = Entrez Gene: GBA2 glucosidase, beta (bile acid) 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57704| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Land A, Braakman I |title=Folding of the human immunodeficiency virus type 1 envelope glycoprotein in the endoplasmic reticulum. |journal=Biochimie |volume=83 |issue= 8 |pages= 783-90 |year= 2001 |pmid= 11530211 |doi=
*cite journal | author=Feizi T, Larkin M |title=AIDS and glycosylation. |journal=Glycobiology |volume=1 |issue= 1 |pages= 17-23 |year= 1992 |pmid= 2136376 |doi=
*cite journal | author=Boot RG, Verhoek M, Donker-Koopman W, "et al." |title=Identification of the non-lysosomal glucosylceramidase as beta-glucosidase 2. |journal=J. Biol. Chem. |volume=282 |issue= 2 |pages= 1305-12 |year= 2007 |pmid= 17105727 |doi= 10.1074/jbc.M610544200
*cite journal | author=Wolk T, Schreiber M |title=N-Glycans in the gp120 V1/V2 domain of the HIV-1 strain NL4-3 are indispensable for viral infectivity and resistance against antibody neutralization. |journal=Med. Microbiol. Immunol. |volume=195 |issue= 3 |pages= 165-72 |year= 2007 |pmid= 16547752 |doi= 10.1007/s00430-006-0016-z
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Humphray SJ, Oliver K, Hunt AR, "et al." |title=DNA sequence and analysis of human chromosome 9. |journal=Nature |volume=429 |issue= 6990 |pages= 369-74 |year= 2004 |pmid= 15164053 |doi= 10.1038/nature02465
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Pantophlet R, Wilson IA, Burton DR |title=Hyperglycosylated mutants of human immunodeficiency virus (HIV) type 1 monomeric gp120 as novel antigens for HIV vaccine design. |journal=J. Virol. |volume=77 |issue= 10 |pages= 5889-901 |year= 2003 |pmid= 12719582 |doi=
*cite journal | author=Hart ML, Saifuddin M, Spear GT |title=Glycosylation inhibitors and neuraminidase enhance human immunodeficiency virus type 1 binding and neutralization by mannose-binding lectin. |journal=J. Gen. Virol. |volume=84 |issue= Pt 2 |pages= 353-60 |year= 2003 |pmid= 12560567 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Matern H, Boermans H, Lottspeich F, Matern S |title=Molecular cloning and expression of human bile acid beta-glucosidase. |journal=J. Biol. Chem. |volume=276 |issue= 41 |pages= 37929-33 |year= 2001 |pmid= 11489889 |doi= 10.1074/jbc.M104290200
*cite journal | author=Nagase T, Kikuno R, Nakayama M, "et al." |title=Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=7 |issue= 4 |pages= 273-81 |year= 2001 |pmid= 10997877 |doi=
*cite journal | author=Matern H, Heinemann H, Legler G, Matern S |title=Purification and characterization of a microsomal bile acid beta-glucosidase from human liver. |journal=J. Biol. Chem. |volume=272 |issue= 17 |pages= 11261-7 |year= 1997 |pmid= 9111029 |doi=
*cite journal | author=Papandreou MJ, Fenouillet E |title=Effect of various glycosidase treatments on the resistance of the HIV-1 envelope to degradation. |journal=FEBS Lett. |volume=406 |issue= 1-2 |pages= 191-5 |year= 1997 |pmid= 9109416 |doi=
*cite journal | author=Bolmstedt A, Sjölander S, Hansen JE, "et al." |title=Influence of N-linked glycans in V4-V5 region of human immunodeficiency virus type 1 glycoprotein gp160 on induction of a virus-neutralizing humoral response. |journal=J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. |volume=12 |issue= 3 |pages= 213-20 |year= 1996 |pmid= 8673525 |doi=
*cite journal | author=Yeh JC, Seals JR, Murphy CI, "et al." |title=Site-specific N-glycosylation and oligosaccharide structures of recombinant HIV-1 gp120 derived from a baculovirus expression system. |journal=Biochemistry |volume=32 |issue= 41 |pages= 11087-99 |year= 1993 |pmid= 8218172 |doi=
*cite journal | author=Fenouillet E, Jones I, Powell B, "et al." |title=Functional role of the glycan cluster of the human immunodeficiency virus type 1 transmembrane glycoprotein (gp41) ectodomain. |journal=J. Virol. |volume=67 |issue= 1 |pages= 150-60 |year= 1993 |pmid= 8093218 |doi=
*cite journal | author=Montefiori DC, Robinson WE, Mitchell WM |title=Role of protein N-glycosylation in pathogenesis of human immunodeficiency virus type 1. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=85 |issue= 23 |pages= 9248-52 |year= 1988 |pmid= 3264072 |doi=
*cite journal | author=Blough HA, Pauwels R, De Clercq E, "et al." |title=Glycosylation inhibitors block the expression of LAV/HTLV-III (HIV) glycoproteins. |journal=Biochem. Biophys. Res. Commun. |volume=141 |issue= 1 |pages= 33-8 |year= 1987 |pmid= 3099781 |doi=

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