MTUS1

Mitochondrial tumor suppressor 1, also known as MTUS1, is a human gene.cite web | title = Entrez Gene: MTUS1 mitochondrial tumor suppressor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57509| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways.cite web | title = Entrez Gene: MTUS1 mitochondrial tumor suppressor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57509| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Di Benedetto M, Pineau P, Nouet S, "et al." |title=Mutation analysis of the 8p22 candidate tumor suppressor gene ATIP/MTUS1 in hepatocellular carcinoma. |journal=Mol. Cell. Endocrinol. |volume=252 |issue= 1-2 |pages= 207-15 |year= 2006 |pmid= 16650523 |doi= 10.1016/j.mce.2006.03.014
*cite journal | author=Frank B, Bermejo JL, Hemminki K, "et al." |title=Copy number variant in the candidate tumor suppressor gene MTUS1 and familial breast cancer risk. |journal=Carcinogenesis |volume=28 |issue= 7 |pages= 1442-5 |year= 2007 |pmid= 17301065 |doi= 10.1093/carcin/bgm033
*cite journal | author=Di Benedetto M, Bièche I, Deshayes F, "et al." |title=Structural organization and expression of human MTUS1, a candidate 8p22 tumor suppressor gene encoding a family of angiotensin II AT2 receptor-interacting proteins, ATIP. |journal=Gene |volume=380 |issue= 2 |pages= 127-36 |year= 2006 |pmid= 16887298 |doi= 10.1016/j.gene.2006.05.021
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Nouet S, Amzallag N, Li JM, "et al." |title=Trans-inactivation of receptor tyrosine kinases by novel angiotensin II AT2 receptor-interacting protein, ATIP. |journal=J. Biol. Chem. |volume=279 |issue= 28 |pages= 28989-97 |year= 2004 |pmid= 15123706 |doi= 10.1074/jbc.M403880200
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Seibold S, Rudroff C, Weber M, "et al." |title=Identification of a new tumor suppressor gene located at chromosome 8p21.3-22. |journal=FASEB J. |volume=17 |issue= 9 |pages= 1180-2 |year= 2003 |pmid= 12692079 |doi= 10.1096/fj.02-0934fje
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Nagase T, Ishikawa K, Kikuno R, "et al." |title=Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=6 |issue= 5 |pages= 337-45 |year= 2000 |pmid= 10574462 |doi=

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