SKIP

SKIP

Skeletal muscle and kidney enriched inositol phosphatase, also known as SKIP, is a human gene.cite web | title = Entrez Gene: SKIP skeletal muscle and kidney enriched inositol phosphatase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51763| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a protein with 5-phosphatase activity toward polyphosphate inositol. The protein localizes to the cytosol in regions lacking actin stress fibers. It is thought that this protein may negatively regulate the actin cytoskeleton. Alternative splicing of this gene results in two transcript variants encoding different isoforms.cite web | title = Entrez Gene: SKIP skeletal muscle and kidney enriched inositol phosphatase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51763| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Drayer AL, Pesesse X, De Smedt F, "et al." |title=The family of inositol and phosphatidylinositol polyphosphate 5-phosphatases. |journal=Biochem. Soc. Trans. |volume=24 |issue= 4 |pages= 1001-5 |year= 1997 |pmid= 8968500 |doi=
*cite journal | author=Mitchell CA, Brown S, Campbell JK, "et al." |title=Regulation of second messengers by the inositol polyphosphate 5-phosphatases. |journal=Biochem. Soc. Trans. |volume=24 |issue= 4 |pages= 994-1000 |year= 1997 |pmid= 8968499 |doi=
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Chen J, Xu J, Zhao W, "et al." |title=Characterization of human LNX, a novel ligand of Numb protein X that is downregulated in human gliomas. |journal=Int. J. Biochem. Cell Biol. |volume=37 |issue= 11 |pages= 2273-83 |year= 2005 |pmid= 16002321 |doi= 10.1016/j.biocel.2005.02.028
*cite journal | author=Cardoso C, Leventer RJ, Ward HL, "et al." |title=Refinement of a 400-kb critical region allows genotypic differentiation between isolated lissencephaly, Miller-Dieker syndrome, and other phenotypes secondary to deletions of 17p13.3. |journal=Am. J. Hum. Genet. |volume=72 |issue= 4 |pages= 918-30 |year= 2003 |pmid= 12621583 |doi=
*cite journal | author=Ijuin T, Takenawa T |title=SKIP negatively regulates insulin-induced GLUT4 translocation and membrane ruffle formation. |journal=Mol. Cell. Biol. |volume=23 |issue= 4 |pages= 1209-20 |year= 2003 |pmid= 12556481 |doi=
*cite journal | author=Gurung R, Tan A, Ooms LM, "et al." |title=Identification of a novel domain in two mammalian inositol-polyphosphate 5-phosphatases that mediates membrane ruffle localization. The inositol 5-phosphatase skip localizes to the endoplasmic reticulum and translocates to membrane ruffles following epidermal growth factor stimulation. |journal=J. Biol. Chem. |volume=278 |issue= 13 |pages= 11376-85 |year= 2003 |pmid= 12536145 |doi= 10.1074/jbc.M209991200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ijuin T, Mochizuki Y, Fukami K, "et al." |title=Identification and characterization of a novel inositol polyphosphate 5-phosphatase. |journal=J. Biol. Chem. |volume=275 |issue= 15 |pages= 10870-5 |year= 2000 |pmid= 10753883 |doi=

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes


Wikimedia Foundation. 2010.

Игры ⚽ Поможем сделать НИР
Synonyms:

Look at other dictionaries:

  • skip — skip …   Dictionnaire des rimes

  • Skip-Bo — Daten zum Spiel Verlag The Skip bo Company (1967), International Games (1980), Amigo (1987), Mattel (1992) Erscheinungsjahr 1967, 1980, 1987, 1992 Art …   Deutsch Wikipedia

  • Skip — ist ein in Nordamerika gebräuchlicher männlicher Vorname. Bekannte Träger sind: Skip Battin (1934–2003), Countrymusiker Skip Ewing (* 1964), Countrymusiker Skip James (1902–1969), Bluesmusiker Skip Spence (1946–1999), Rockmusiker Skip steht für:… …   Deutsch Wikipedia

  • skip — ● skip nom masculin (anglais skip, benne) Appareil élévateur constitué par une benne de grande capacité, mue par un treuil, dont le vidage s opère par basculement ou par ouverture du fond. (On l utilise pour l alimentation des fours verticaux et… …   Encyclopédie Universelle

  • SKIP-BO — SKIP BO(IPAEng|skɪpˈ boʊ) is a popular card game. In 1967, Ms. Hazel Bowman of Brownfield, Texas began producing a boxed edition of the game under the name Skip bo. International Games, Inc. purchased the game in 1980. The company was… …   Wikipedia

  • Skip — Skip, v. t. 1. To leap lightly over; as, to skip the rope. [1913 Webster] 2. To pass over or by without notice; to omit; to miss; as, to skip a line in reading; to skip a lesson. [1913 Webster] They who have a mind to see the issue may skip these …   The Collaborative International Dictionary of English

  • Skip-It — is a children s toy invented by Victor Petrusek and manufactured by Tiger Electronics. During its initial release in the late 1980s, the Skip It apparatus became a commercial success through its avid advertisements on daytime Nickelodeon… …   Wikipedia

  • SKIP — – Das Kinomagazin Beschreibung österreichische Filmzeitschrift Erstausgabe 1983 Erscheinungsweise …   Deutsch Wikipedia

  • skip it — spoken phrase used for telling someone that you do not want to talk about something If you were about to ask me for money, skip it! Thesaurus: ways of saying that you don t want to talk or think about somethingsynonym Main entry: skip * * * skip… …   Useful english dictionary

  • skip — skip1 [skip] vi. skipped, skipping [ME skippen, prob. < Scand form akin to ON skopa, to jump, run < IE * skeub , to shoot, throw > SHOVE] 1. to leap, jump, or spring lightly; specif., to move along by hopping lightly on first one foot… …   English World dictionary

  • Skip — Skip, v. i. [imp. & p. p. {Skipped}; p. pr. & vb. n. {Skipping}.] [OE. skippen, of uncertain origin; cf. Icel. skopa run, skoppa to spin like a top, OSw. & dial. Sw. skimmpa to run, skimpa, skompa, to hop, skip; or Ir. sgiob to snatch, Gael.… …   The Collaborative International Dictionary of English

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”