- PIGH
Phosphatidylinositol glycan anchor biosynthesis, class H, also known as PIGH, is a human
gene .cite web | title = Entrez Gene: PIGH phosphatidylinositol glycan anchor biosynthesis, class H| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5283| accessdate = ]PBB_Summary
section_title =
summary_text = This gene encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. The protein encoded by this gene is a subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum.cite web | title = Entrez Gene: PIGH phosphatidylinositol glycan anchor biosynthesis, class H| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5283| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Suzuki Y, Yamashita R, Shirota M, "et al." |title=Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. |journal=Genome Res. |volume=14 |issue= 9 |pages= 1711-8 |year= 2004 |pmid= 15342556 |doi= 10.1101/gr.2435604
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Watanabe R, Inoue N, Westfall B, "et al." |title=The first step of glycosylphosphatidylinositol biosynthesis is mediated by a complex of PIG-A, PIG-H, PIG-C and GPI1. |journal=EMBO J. |volume=17 |issue= 4 |pages= 877-85 |year= 1998 |pmid= 9463366 |doi= 10.1093/emboj/17.4.877
*cite journal | author=Watanabe R, Kinoshita T, Masaki R, "et al." |title=PIG-A and PIG-H, which participate in glycosylphosphatidylinositol anchor biosynthesis, form a protein complex in the endoplasmic reticulum. |journal=J. Biol. Chem. |volume=271 |issue= 43 |pages= 26868-75 |year= 1996 |pmid= 8900170 |doi=
*cite journal | author=Kamitani T, Chang HM, Rollins C, "et al." |title=Correction of the class H defect in glycosylphosphatidylinositol anchor biosynthesis in Ltk- cells by a human cDNA clone. |journal=J. Biol. Chem. |volume=268 |issue= 28 |pages= 20733-6 |year= 1993 |pmid= 8407896 |doi=
*cite journal | author=Ware RE, Howard TA, Kamitani T, "et al." |title=Chromosomal assignment of genes involved in glycosylphosphatidylinositol anchor biosynthesis: implications for the pathogenesis of paroxysmal nocturnal hemoglobinuria. |journal=Blood |volume=83 |issue= 12 |pages= 3753-7 |year= 1994 |pmid= 8204896 |doi=PBB_Controls
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