- TAF9B
TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa, also known as TAF9B, is a human
gene .cite web | title = Entrez Gene: TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51616| accessdate = ]PBB_Summary
section_title =
summary_text = Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that is similar to one of the small subunits of TFIID, TBP-associated factor 9, and is also a subunit of TFIID. TAF9 and TAF9b share some functions but also have distinct roles in the transcriptional regulatory process.cite web | title = Entrez Gene: TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51616| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Albright SR, Tjian R |title=TAFs revisited: more data reveal new twists and confirm old ideas. |journal=Gene |volume=242 |issue= 1-2 |pages= 1-13 |year= 2000 |pmid= 10721692 |doi=
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Frontini M, Soutoglou E, Argentini M, "et al." |title=TAF9b (formerly TAF9L) is a bona fide TAF that has unique and overlapping roles with TAF9. |journal=Mol. Cell. Biol. |volume=25 |issue= 11 |pages= 4638-49 |year= 2005 |pmid= 15899866 |doi= 10.1128/MCB.25.11.4638-4649.2005
*cite journal | author=Ross MT, Grafham DV, Coffey AJ, "et al." |title=The DNA sequence of the human X chromosome. |journal=Nature |volume=434 |issue= 7031 |pages= 325-37 |year= 2005 |pmid= 15772651 |doi= 10.1038/nature03440
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Chen Z, Manley JL |title=In vivo functional analysis of the histone 3-like TAF9 and a TAF9-related factor, TAF9L. |journal=J. Biol. Chem. |volume=278 |issue= 37 |pages= 35172-83 |year= 2003 |pmid= 12837753 |doi= 10.1074/jbc.M304241200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Lu H, Levine AJ |title=Human TAFII31 protein is a transcriptional coactivator of the p53 protein. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=92 |issue= 11 |pages= 5154-8 |year= 1995 |pmid= 7761466 |doi=PBB_Controls
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