CD180

CD180 molecule, also known as CD180, is a human gene.cite web | title = Entrez Gene: CD180 CD180 molecule| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4064| accessdate = ]

PBB_Summary
section_title =
summary_text = CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria.cite web | title = Entrez Gene: CD180 CD180 molecule| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4064| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Honda Y, Yamagiwa S, Matsuda Y, "et al." |title=Altered expression of TLR homolog RP105 on monocytes hypersensitive to LPS in patients with primary biliary cirrhosis. |journal=J. Hepatol. |volume=47 |issue= 3 |pages= 404–11 |year= 2007 |pmid= 17448566 |doi= 10.1016/j.jhep.2007.03.012
*cite journal | author=Divanovic S, Trompette A, Atabani SF, "et al." |title=Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105. |journal=Nat. Immunol. |volume=6 |issue= 6 |pages= 571–8 |year= 2005 |pmid= 15852007 |doi= 10.1038/ni1198
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Suzuki Y, Yamashita R, Shirota M, "et al." |title=Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. |journal=Genome Res. |volume=14 |issue= 9 |pages= 1711–8 |year= 2004 |pmid= 15342556 |doi= 10.1101/gr.2435604
*cite journal | author=Zhang Z, Henzel WJ |title=Signal peptide prediction based on analysis of experimentally verified cleavage sites. |journal=Protein Sci. |volume=13 |issue= 10 |pages= 2819–24 |year= 2005 |pmid= 15340161 |doi= 10.1110/ps.04682504
*cite journal | author=Izmailova E, Bertley FM, Huang Q, "et al." |title=HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages. |journal=Nat. Med. |volume=9 |issue= 2 |pages= 191–7 |year= 2003 |pmid= 12539042 |doi= 10.1038/nm822
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Miura Y, Shimazu R, Miyake K, "et al." |title=RP105 is associated with MD-1 and transmits an activation signal in human B cells. |journal=Blood |volume=92 |issue= 8 |pages= 2815–22 |year= 1998 |pmid= 9763566 |doi=
*cite journal | author=Miyake K, Shimazu R, Kondo J, "et al." |title=Mouse MD-1, a molecule that is physically associated with RP105 and positively regulates its expression. |journal=J. Immunol. |volume=161 |issue= 3 |pages= 1348–53 |year= 1998 |pmid= 9686597 |doi=
*cite journal | author=Miura Y, Miyake K, Yamashita Y, "et al." |title=Molecular cloning of a human RP105 homologue and chromosomal localization of the mouse and human RP105 genes (Ly64 and LY64). |journal=Genomics |volume=38 |issue= 3 |pages= 299–304 |year= 1997 |pmid= 8975706 |doi= 10.1006/geno.1996.0632

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes