LAIR2

Leukocyte-associated immunoglobulin-like receptor 2, also known as LAIR2, is a human gene.cite web | title = Entrez Gene: LAIR2 leukocyte-associated immunoglobulin-like receptor 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3904| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the immunoglobulin superfamily. It was identified by its similarity to LAIR1, an inhibitory receptor present on mononuclear leukocytes. This gene maps to a region of 19q13.4, termed the leukocyte receptor cluster, which contains 29 genes in the immunoglobulin superfamily, including LAIR1. The function of this protein is unknown, although it is thought to be secreted and may help modulate mucosal tolerance. Two transcript variants encoding different isoforms have been found for this gene.cite web | title = Entrez Gene: LAIR2 leukocyte-associated immunoglobulin-like receptor 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3904| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Lebbink RJ, van den Berg MC, de Ruiter T, "et al." |title=The soluble leukocyte-associated Ig-like receptor (LAIR)-2 antagonizes the collagen/LAIR-1 inhibitory immune interaction. |journal=J. Immunol. |volume=180 |issue= 3 |pages= 1662–9 |year= 2008 |pmid= 18209062 |doi=
*cite journal | author=Denoeud F, Kapranov P, Ucla C, "et al." |title=Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions. |journal=Genome Res. |volume=17 |issue= 6 |pages= 746–59 |year= 2007 |pmid= 17567994 |doi= 10.1101/gr.5660607
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Meyaard L, van der Vuurst de Vries AR, de Ruiter T, "et al." |title=The epithelial cellular adhesion molecule (Ep-CAM) is a ligand for the leukocyte-associated immunoglobulin-like receptor (LAIR). |journal=J. Exp. Med. |volume=194 |issue= 1 |pages= 107–12 |year= 2001 |pmid= 11435477 |doi=
*cite journal | author=Wende H, Volz A, Ziegler A |title=Extensive gene duplications and a large inversion characterize the human leukocyte receptor cluster. |journal=Immunogenetics |volume=51 |issue= 8-9 |pages= 703–13 |year= 2000 |pmid= 10941842 |doi=
*cite journal | author=Meyaard L, Hurenkamp J, Clevers H, "et al." |title=Leukocyte-associated Ig-like receptor-1 functions as an inhibitory receptor on cytotoxic T cells. |journal=J. Immunol. |volume=162 |issue= 10 |pages= 5800–4 |year= 1999 |pmid= 10229813 |doi=
*cite journal | author=Meyaard L, Adema GJ, Chang C, "et al." |title=LAIR-1, a novel inhibitory receptor expressed on human mononuclear leukocytes. |journal=Immunity |volume=7 |issue= 2 |pages= 283–90 |year= 1997 |pmid= 9285412 |doi=
*cite journal | author=Hillier LD, Lennon G, Becker M, "et al." |title=Generation and analysis of 280,000 human expressed sequence tags. |journal=Genome Res. |volume=6 |issue= 9 |pages= 807–28 |year= 1997 |pmid= 8889549 |doi=

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