TXN2

Thioredoxin 2, also known as TXN2, is a human gene.cite web | title = Entrez Gene: TXN2 thioredoxin 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=25828| accessdate = ]

PBB_Summary
section_title =
summary_text = This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis.cite web | title = Entrez Gene: TXN2 thioredoxin 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=25828| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Wang Z, Zhang H, Li XF, Le XC |title=Study of interactions between arsenicals and thioredoxins (human and E. coli) using mass spectrometry. |journal=Rapid Commun. Mass Spectrom. |volume=21 |issue= 22 |pages= 3658–66 |year= 2007 |pmid= 17939155 |doi= 10.1002/rcm.3263
*cite journal | author=Udler M, Maia AT, Cebrian A, "et al." |title=Common germline genetic variation in antioxidant defense genes and survival after diagnosis of breast cancer. |journal=J. Clin. Oncol. |volume=25 |issue= 21 |pages= 3015–23 |year= 2007 |pmid= 17634480 |doi= 10.1200/JCO.2006.10.0099
*cite journal | author=Zhang H, Go YM, Jones DP |title=Mitochondrial thioredoxin-2/peroxiredoxin-3 system functions in parallel with mitochondrial GSH system in protection against oxidative stress. |journal=Arch. Biochem. Biophys. |volume=465 |issue= 1 |pages= 119–26 |year= 2007 |pmid= 17548047 |doi= 10.1016/j.abb.2007.05.001
*cite journal | author=Zhou J, Damdimopoulos AE, Spyrou G, Brüne B |title=Thioredoxin 1 and thioredoxin 2 have opposed regulatory functions on hypoxia-inducible factor-1alpha. |journal=J. Biol. Chem. |volume=282 |issue= 10 |pages= 7482–90 |year= 2007 |pmid= 17220299 |doi= 10.1074/jbc.M608289200
*cite journal | author=Oestergaard MZ, Tyrer J, Cebrian A, "et al." |title=Interactions between genes involved in the antioxidant defence system and breast cancer risk. |journal=Br. J. Cancer |volume=95 |issue= 4 |pages= 525–31 |year= 2006 |pmid= 16868544 |doi= 10.1038/sj.bjc.6603272
*cite journal | author=Cebrian A, Pharoah PD, Ahmed S, "et al." |title=Tagging single-nucleotide polymorphisms in antioxidant defense enzymes and susceptibility to breast cancer. |journal=Cancer Res. |volume=66 |issue= 2 |pages= 1225–33 |year= 2006 |pmid= 16424062 |doi= 10.1158/0008-5472.CAN-05-1857
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Collins JE, Wright CL, Edwards CA, "et al." |title=A genome annotation-driven approach to cloning the human ORFeome. |journal=Genome Biol. |volume=5 |issue= 10 |pages= R84 |year= 2005 |pmid= 15461802 |doi= 10.1186/gb-2004-5-10-r84
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Damdimopoulos AE, Miranda-Vizuete A, Pelto-Huikko M, "et al." |title=Human mitochondrial thioredoxin. Involvement in mitochondrial membrane potential and cell death. |journal=J. Biol. Chem. |volume=277 |issue= 36 |pages= 33249–57 |year= 2002 |pmid= 12080052 |doi= 10.1074/jbc.M203036200
*cite journal | author=Chen Y, Cai J, Murphy TJ, Jones DP |title=Overexpressed human mitochondrial thioredoxin confers resistance to oxidant-induced apoptosis in human osteosarcoma cells. |journal=J. Biol. Chem. |volume=277 |issue= 36 |pages= 33242–8 |year= 2002 |pmid= 12032145 |doi= 10.1074/jbc.M202026200
*cite journal | author=Dunham I, Shimizu N, Roe BA, "et al." |title=The DNA sequence of human chromosome 22. |journal=Nature |volume=402 |issue= 6761 |pages= 489–95 |year= 1999 |pmid= 10591208 |doi= 10.1038/990031
*cite journal | author=Spyrou G, Enmark E, Miranda-Vizuete A, Gustafsson J |title=Cloning and expression of a novel mammalian thioredoxin. |journal=J. Biol. Chem. |volume=272 |issue= 5 |pages= 2936–41 |year= 1997 |pmid= 9006939 |doi=

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