GSPT2

G1 to S phase transition 2, also known as GSPT2, is a human gene.cite web | title = Entrez Gene: GSPT2 G1 to S phase transition 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23708| accessdate = ]

PBB_Summary
section_title =
summary_text = GSPT2 is closely related to GSPT1 (MIM 139259), a GTP-binding protein that plays an essential role at the G1- to S-phase transition of the cell cycle in yeast and human cells. GSPT1 is a positive regulator of translational accuracy and, in a binary complex with eRF1 (MIM 600285), functions as a polypeptide chain release factor. [supplied by OMIM] cite web | title = Entrez Gene: GSPT2 G1 to S phase transition 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23708| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Chauvin C, Salhi S, Le Goff C, "et al." |title=Involvement of human release factors eRF3a and eRF3b in translation termination and regulation of the termination complex formation. |journal=Mol. Cell. Biol. |volume=25 |issue= 14 |pages= 5801–11 |year= 2005 |pmid= 15987998 |doi= 10.1128/MCB.25.14.5801-5811.2005
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Le Goff C, Zemlyanko O, Moskalenko S, "et al." |title=Mouse GSPT2, but not GSPT1, can substitute for yeast eRF3 in vivo. |journal=Genes Cells |volume=7 |issue= 10 |pages= 1043–57 |year= 2003 |pmid= 12354098 |doi=
*cite journal | author=Hansen LL, Jakobsen CG, Justesen J |title=Assignment of the human peptide chain release factor 3 (GSPT2) to Xp11.23-->p11.21 and of the distal marker DXS1039 by radiation hybrid mapping. |journal=Cytogenet. Cell Genet. |volume=86 |issue= 3-4 |pages= 250–1 |year= 2000 |pmid= 10575220 |doi=
*cite journal | author=Hoshino S, Imai M, Kobayashi T, "et al." |title=The eukaryotic polypeptide chain releasing factor (eRF3/GSPT) carrying the translation termination signal to the 3'-Poly(A) tail of mRNA. Direct association of erf3/GSPT with polyadenylate-binding protein. |journal=J. Biol. Chem. |volume=274 |issue= 24 |pages= 16677–80 |year= 1999 |pmid= 10358005 |doi=
*cite journal | author=Hoshino S, Imai M, Mizutani M, "et al." |title=Molecular cloning of a novel member of the eukaryotic polypeptide chain-releasing factors (eRF). Its identification as eRF3 interacting with eRF1. |journal=J. Biol. Chem. |volume=273 |issue= 35 |pages= 22254–9 |year= 1998 |pmid= 9712840 |doi=

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