ANP32C

Acidic (leucine-rich) nuclear phosphoprotein 32 family, member C, also known as ANP32C, is a human gene.cite web | title = Entrez Gene: ANP32C acidic (leucine-rich) nuclear phosphoprotein 32 family, member C| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23520| accessdate = ]

PBB_Summary
section_title =
summary_text = Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is divergent between PP32 and the protein encoded by this gene. This gene does not contain introns.cite web | title = Entrez Gene: ANP32C acidic (leucine-rich) nuclear phosphoprotein 32 family, member C| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23520| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Matilla A, Radrizzani M |title=The Anp32 family of proteins containing leucine-rich repeats. |journal=Cerebellum |volume=4 |issue= 1 |pages= 7–18 |year= 2005 |pmid= 15895553 |doi=
*cite journal | author=Kochevar GJ, Brody JR, Kadkol SS, "et al." |title=Identification of a functional mutation in pp32r1 (ANP32C). |journal=Hum. Mutat. |volume=23 |issue= 6 |pages= 546–51 |year= 2004 |pmid= 15146458 |doi= 10.1002/humu.20030
*cite journal | author=Fan Z, Beresford PJ, Zhang D, "et al." |title=Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A. |journal=Nat. Immunol. |volume=4 |issue= 2 |pages= 145–53 |year= 2003 |pmid= 12524539 |doi= 10.1038/ni885
*cite journal | author=Kadkol SS, El Naga GA, Brody JR, "et al." |title=Expression of pp32 gene family members in breast cancer. |journal=Breast Cancer Res. Treat. |volume=68 |issue= 1 |pages= 65–73 |year= 2002 |pmid= 11678310 |doi=
*cite journal | author=Bai J, Brody JR, Kadkol SS, Pasternack GR |title=Tumor suppression and potentiation by manipulation of pp32 expression. |journal=Oncogene |volume=20 |issue= 17 |pages= 2153–60 |year= 2001 |pmid= 11360199 |doi= 10.1038/sj.onc.1204294
*cite journal | author=Kadkol SS, Brody JR, Pevsner J, "et al." |title=Correction to "Modulation of oncogenic potential by alternative gene use in human prostate cancer" |journal=Nat. Med. |volume=5 |issue= 9 |pages= 1087 |year= |pmid= 10471270 |doi= 10.1038/12530
*cite journal | author=Brody JR, Kadkol SS, Mahmoud MA, "et al." |title=Identification of sequences required for inhibition of oncogene-mediated transformation by pp32. |journal=J. Biol. Chem. |volume=274 |issue= 29 |pages= 20053–5 |year= 1999 |pmid= 10400610 |doi=
*cite journal | author=Kadkol SS, Brody JR, Pevsner J, "et al." |title=Modulation of oncogenic potential by alternative gene use in human prostate cancer. |journal=Nat. Med. |volume=5 |issue= 3 |pages= 275–9 |year= 1999 |pmid= 10086381 |doi= 10.1038/6488

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