CENTD1

CENTD1

Centaurin, delta 1, also known as CENTD1, is a human gene.cite web | title = Entrez Gene: CENTD1 centaurin, delta 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=116984| accessdate = ]

PBB_Summary
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summary_text = The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. This protein lacks the predicted catalytic arginine in the RHO-GAP domain and is therefore unlikely to have RHO-GAP activity. While the encoded protein does contain a sterile alpha motif (SAM) commonly found in some signaling molecules, the function of the protein has not been determined. Two transcript variants encoding different isoforms have been found for this gene.cite web | title = Entrez Gene: CENTD1 centaurin, delta 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=116984| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026
*cite journal | author=Yoon HY, Miura K, Cuthbert EJ, "et al." |title=ARAP2 effects on the actin cytoskeleton are dependent on Arf6-specific GTPase-activating-protein activity and binding to RhoA-GTP. |journal=J. Cell. Sci. |volume=119 |issue= Pt 22 |pages= 4650–66 |year= 2007 |pmid= 17077126 |doi= 10.1242/jcs.03237
*cite journal | author=Hillier LW, Graves TA, Fulton RS, "et al." |title=Generation and annotation of the DNA sequences of human chromosomes 2 and 4. |journal=Nature |volume=434 |issue= 7034 |pages= 724–31 |year= 2005 |pmid= 15815621 |doi= 10.1038/nature03466
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Miura K, Jacques KM, Stauffer S, "et al." |title=ARAP1: a point of convergence for Arf and Rho signaling. |journal=Mol. Cell |volume=9 |issue= 1 |pages= 109–19 |year= 2002 |pmid= 11804590 |doi=
*cite journal | author=Krugmann S, Anderson KE, Ridley SH, "et al." |title=Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices. |journal=Mol. Cell |volume=9 |issue= 1 |pages= 95–108 |year= 2002 |pmid= 11804589 |doi=
*cite journal | author= |title=Toward a complete human genome sequence. |journal=Genome Res. |volume=8 |issue= 11 |pages= 1097–108 |year= 1999 |pmid= 9847074 |doi=
*cite journal | author=Nagase T, Ishikawa K, Miyajima N, "et al." |title=Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. |journal=DNA Res. |volume=5 |issue= 1 |pages= 31–9 |year= 1998 |pmid= 9628581 |doi=

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  • Pleckstrin homology domain — Pfam box Symbol = PH Name = width =250 caption =PH domain of tyrosine protein kinase BTK Pfam= PF00169 InterPro= IPR001849 SMART= PH PROSITE=PDOC50003 SCOP = 1dyn TCDB = OPM family= 51 OPM protein= 1pls PDB=PDB3|1dynB:520 625 PDB3|2dynA:520 625… …   Wikipedia

  • RhoGAP domain — Pfam box Symbol = RhoGAP Name = RhoGAP domain width = caption = Pfam= PF00620 InterPro= IPR000198 SMART= RhoGAP PROSITE= PDOC50238 SCOP = 1rgb TCDB = OPM family= OPM protein= 1xa6 PDB=PDB3|1xa6A:291 444 PDB3|1f7cA:199 355 PDB3|1am4B:260… …   Wikipedia

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