PHACTR3

PHACTR3

Phosphatase and actin regulator 3, also known as PHACTR3, is a human gene.cite web | title = Entrez Gene: PHACTR3 phosphatase and actin regulator 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=116154| accessdate = ]

PBB_Summary
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summary_text = The protein encoded by this gene is associated with the nuclear scaffold in proliferating cells. It was found to bind to the catalytic subunit of protein phosphatase-1 (PP1) and inhibit PP1 activity, suggesting that this protein may function as a regulatory subunit of PP1. Alternative splicing at this locus results in several transcript variants encoding different isoforms.cite web | title = Entrez Gene: PHACTR3 phosphatase and actin regulator 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=116154| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Worch S, Fiedler E, Hansmann I, Schlote D |title=Genomic organization and expression pattern of scapinin (PHACTR3) in mouse and human. |journal=Cytogenet. Genome Res. |volume=115 |issue= 1 |pages= 23–9 |year= 2006 |pmid= 16974080 |doi= 10.1159/000094797
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Colland F, Jacq X, Trouplin V, "et al." |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324–32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104
*cite journal | author=Allen PB, Greenfield AT, Svenningsson P, "et al." |title=Phactrs 1-4: A family of protein phosphatase 1 and actin regulatory proteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 18 |pages= 7187–92 |year= 2004 |pmid= 15107502 |doi= 10.1073/pnas.0401673101
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Sagara J, Higuchi T, Hattori Y, "et al." |title=Scapinin, a putative protein phosphatase-1 regulatory subunit associated with the nuclear nonchromatin structure. |journal=J. Biol. Chem. |volume=278 |issue= 46 |pages= 45611–9 |year= 2003 |pmid= 12925532 |doi= 10.1074/jbc.M305227200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Deloukas P, Matthews LH, Ashurst J, "et al." |title=The DNA sequence and comparative analysis of human chromosome 20. |journal=Nature |volume=414 |issue= 6866 |pages= 865–71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a

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