- GPA33
Glycoprotein A33 (transmembrane), also known as GPA33, is a human
gene .cite web | title = Entrez Gene: GPA33 glycoprotein A33 (transmembrane)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10223| accessdate = ]PBB_Summary
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summary_text = The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily.cite web | title = Entrez Gene: GPA33 glycoprotein A33 (transmembrane)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10223| accessdate = ]References
Further reading
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citations =
*cite journal | author=Hwang SH, Sohn YH, Oh HB, "et al." |title=Human leukocyte antigen alleles and haplotypes associated with chronicity of hepatitis B virus infection in Koreans. |journal=Arch. Pathol. Lab. Med. |volume=131 |issue= 1 |pages= 117–21 |year= 2007 |pmid= 17227111 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Mao Z, Song S, Zhu Y, "et al." |title=Transcriptional regulation of A33 antigen expression by gut-enriched Krüppel-like factor. |journal=Oncogene |volume=22 |issue= 28 |pages= 4434–43 |year= 2003 |pmid= 12853980 |doi= 10.1038/sj.onc.1206508
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Johnstone CN, White SJ, Tebbutt NC, "et al." |title=Analysis of the regulation of the A33 antigen gene reveals intestine-specific mechanisms of gene expression. |journal=J. Biol. Chem. |volume=277 |issue= 37 |pages= 34531–9 |year= 2002 |pmid= 12114523 |doi= 10.1074/jbc.M204865200
*cite journal | author=Moritz RL, Ritter G, Catimel B, "et al." |title=Micro-sequencing strategies for the human A33 antigen, a novel surface glycoprotein of human gastrointestinal epithelium. |journal=Journal of chromatography. A |volume=798 |issue= 1-2 |pages= 91–101 |year= 1998 |pmid= 9542130 |doi=
*cite journal | author=Ritter G, Cohen LS, Nice EC, "et al." |title=Characterization of posttranslational modifications of human A33 antigen, a novel palmitoylated surface glycoprotein of human gastrointestinal epithelium. |journal=Biochem. Biophys. Res. Commun. |volume=236 |issue= 3 |pages= 682–6 |year= 1997 |pmid= 9245713 |doi= 10.1006/bbrc.1997.6966
*cite journal | author=Heath JK, White SJ, Johnstone CN, "et al." |title=The human A33 antigen is a transmembrane glycoprotein and a novel member of the immunoglobulin superfamily. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 2 |pages= 469–74 |year= 1997 |pmid= 9012807 |doi=PBB_Controls
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