ACTR1B

ARP1 actin-related protein 1 homolog B, centractin beta (yeast), also known as ACTR1B, is a human gene.cite web | title = Entrez Gene: ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10120| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins are of equal length and share 90% amino acid identity. They are present in a constant ratio of approximately 1:15 in the dynactin complex.cite web | title = Entrez Gene: ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10120| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Hillier LW, Graves TA, Fulton RS, "et al." |title=Generation and annotation of the DNA sequences of human chromosomes 2 and 4. |journal=Nature |volume=434 |issue= 7034 |pages= 724–31 |year= 2005 |pmid= 15815621 |doi= 10.1038/nature03466
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Eckley DM, Schroer TA |title=Interactions between the evolutionarily conserved, actin-related protein, Arp11, actin, and Arp1. |journal=Mol. Biol. Cell |volume=14 |issue= 7 |pages= 2645–54 |year= 2004 |pmid= 12857853 |doi= 10.1091/mbc.E03-01-0049
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Simpson JC, Wellenreuther R, Poustka A, "et al." |title=Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. |journal=EMBO Rep. |volume=1 |issue= 3 |pages= 287–92 |year= 2001 |pmid= 11256614 |doi= 10.1093/embo-reports/kvd058
*cite journal | author=Elsea SH, Clark IB, Juyal RC, "et al." |title=Assignment of beta-centractin (CTRN2) to human chromosome 2 bands q11.1-->q11.2 with somatic cell hybrids and in situ hybridization. |journal=Cytogenet. Cell Genet. |volume=84 |issue= 1-2 |pages= 48–9 |year= 1999 |pmid= 10343100 |doi=
*cite journal | author=Clark SW, Staub O, Clark IB, "et al." |title=Beta-centractin: characterization and distribution of a new member of the centractin family of actin-related proteins. |journal=Mol. Biol. Cell |volume=5 |issue= 12 |pages= 1301–10 |year= 1995 |pmid= 7696711 |doi=
*cite journal | author=Adams MD, Dubnick M, Kerlavage AR, "et al." |title=Sequence identification of 2,375 human brain genes. |journal=Nature |volume=355 |issue= 6361 |pages= 632–4 |year= 1992 |pmid= 1538749 |doi= 10.1038/355632a0

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