- Israel Kleiner
Professor Israel Simon Kleiner (born
April 8 ,1885 , diedJune 15 ,1966 ) was a biochemist whose work helped lead to the discovery ofinsulin .Kleiner's grandparents Israel and Eva (Meyer) came to America from
Bavaria , Germany in 1848. Born inNew Haven, Connecticut , Kleiner was a member of the Congregation Mishkan Israel temple, where his uncle, city council member Charles Kleiner was president.Kleiner received his Ph.D in Biochemistry at
Yale in 1909. From 1910, he worked as an assistant in physiology at theRockefeller Institute , until 1914 when he became an associate. In 1919 he was appointed as Professor at the New York Homeopathic Medical College (later to becomeNew York Medical College ). Here he served as acting Dean in 1921 and then as Dean from 1922-1925. In 1935 he became professor of Biochemistry, and from 1948 was the Director of the Department of Biochemistry.On February 10, 1959, Kleiner was awarded the third annual
Van Slyke award in Clinical Chemistry, at theNew York Academy of Sciences .He was buried near his grandparents at the Congregation Mishkan Israel cemetery, in New Haven, Connecticut.
Insulin
In 1919, at the Rockefeller Institute, Kleiner was one of the first to demonstrate the effect of extracts from the
pancreas on animals, causinghypoglycemia . These were the early efforts which eventually helped lead to the discovery ofinsulin .References
* [http://dels.nas.edu/ilar_n/ilarjournal/45_3/html/v4503barthold.shtml Article: Unsung Heroes in the Battle Against Diabetes]
* [http://www.clinchem.org/cgi/issue_pdf/frontmatter_pdf/5/2.pdf Van Slyke award details]
* [http://en.wikipedia.org/wiki/User_talk:Bogdangiusca/Archive1 A discussion on insulin discoverers]
* [http://www.nymc.edu/alumni/devl/SOM-alumni-connection.asp New York Medical College medal winners (including the 1959 award)]
* [http://jn.nutrition.org/cgi/reprint/92/4/507.pdf Notice of death]
* [http://www.gencircles.com/users/jsondhelm/1/data/140 Genealogy]External links
* [http://www.amazon.com/dp/B0007FKHQ0 Book on Laboratory preparation in Biochemistry]
* [http://www.amazon.com/dp/B0007DOSTE Textbook on Biochemistry authored by Prof. Kleiner]
* [http://patents.ic.gc.ca/cipo/cpd/en/patent/352117/summary.html Canadian patent issued to Prof. Kleiner in 1935]
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