Gated SPECT

Gated SPECT - A nuclear medicine imaging SPECT (Single Photon Emission Computed Tomography) procedure where the ECG (Electrocardiogram) guides the acquisition so that the resulting set of SPECT images shows the heart as it contracts over the interval from one R wave to the next.

The acquisition computer defines the number of time bins or frames to divide the R to R interval of the patient's electrocardiogram. A "window" may be set which discards data from R to R intervals which deviate from some amount from the patient's average R to R wave duration. This discards preventricular contractions and arrhythmias from the acquisition and improves the quality of the resulting study.

The camera will take a series of pictures around the patient, dividing each 'step' of the camera head's motion into the predetermined number of 'frames.' The details of this acquisition vary with single-headed, double-headed, or triple-headed cameras -- but a single-headed camera typically acquires 32 'steps' over an arc of 180 degrees around the patient.

When the acquisition is completed, the technician must process the images (SPECT) to create a data set which represents the volume of tracer as seen by the camera during the study acquisition. In Gated SPECT, this process is performed for each of the time bins defined by the acquisition protocol. When viewed by the physician for interpretation, the heart can be watched as it contracts and expands from Diastole to Systole.

The computer can calculate for the physician the patient's ejection fraction, end diastolic volume, wall motion, end systolic volume, myocardial thickening, shortening, and contractility. It should be noted, however, that one is viewing an average of all collected heart beats over the image acquisition. Noise on the ECG, patient motion, artifacts, or a change in the heart rate during acquisition can degrade the quality of the resulting gated image dataset.

See Also
* [http://brighamrad.harvard.edu/education/online/Cardiac/Gated-SPECT.html| Atlas of Myocardioal Perfusion SPECT]
* [http://www.medscape.com/viewarticle/449487_6| Role of Myocardial Perfusion Imaging in Managing CAD]
* [http://tech.snmjournals.org/cgi/content/full/32/4/179| Gated Myocardial Perfusion SPECT: Basic Principles, Technical Aspects, and Clinical Applications] (note article's references)
* [http://www.csmc.edu/5849.html| Quantitative Gated SPECT (QGS)]