Bisbiguanide

Bisbiguanides are a class of chemically related compounds known for their bactericidal properties. Generally considered to be of the generic formula: R1 R2 N.C(:NR6)NH.C(:NH)NH.CH2 X-- --(CH2)3 NH.C(:NH)NH.C(:NR7)NR3 R4 V [ [http://www.freepatentsonline.com/4670592.html Bisbiguanide compounds - Patent 4670592 ] ] These compounds include the antiseptics alexidine and chlorhexidine. [cite journal |author=Tanzer JM, Slee AM, Kamay BA |title=Structural requirements of guanide, biguanide, and bisbiguanide agents for antiplaque activity |journal=Antimicrob. Agents Chemother. |volume=12 |issue=6 |pages=721–9 |year=1977 |pmid=931371 |url=http://aac.asm.org/cgi/pmidlookup?view=long&pmid=931371 |doi=10.1128/AAC.]

References