CEACAM5

CEACAM5

Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) also known as CD66e (Cluster of Differentiation 66e), is a human gene.cite web | title = Entrez Gene: CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1048| accessdate = ]

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ee also

* Cluster of differentiation

References

Further reading

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*cite journal | author=Willcocks TC, Craig IW |title=Characterization of the genomic organization of human carcinoembryonic antigen (CEA): comparison with other family members and sequence analysis of 5' controlling region. |journal=Genomics |volume=8 |issue= 3 |pages= 492–500 |year= 1991 |pmid= 2286372 |doi=
*cite journal | author=Barnett T, Zimmermann W |title=Workshop report: proposed nomenclature for the carcinoembryonic antigen (CEA) gene family. |journal=Tumour Biol. |volume=11 |issue= 1-2 |pages= 59–63 |year= 1990 |pmid= 2309067 |doi=
*cite journal | author=Schrewe H, Thompson J, Bona M, "et al." |title=Cloning of the complete gene for carcinoembryonic antigen: analysis of its promoter indicates a region conveying cell type-specific expression. |journal=Mol. Cell. Biol. |volume=10 |issue= 6 |pages= 2738–48 |year= 1990 |pmid= 2342461 |doi=
*cite journal | author=Kamarck ME, Elting JJ, Hart JT, "et al." |title=Carcinoembryonic antigen family: expression in a mouse L-cell transfectant and characterization of a partial cDNA in bacteriophage lambda gt11. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=84 |issue= 15 |pages= 5350–4 |year= 1987 |pmid= 2955415 |doi=
*cite journal | author=Zimmermann W, Ortlieb B, Friedrich R, von Kleist S |title=Isolation and characterization of cDNA clones encoding the human carcinoembryonic antigen reveal a highly conserved repeating structure. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=84 |issue= 9 |pages= 2960–4 |year= 1987 |pmid= 3033671 |doi=
*cite journal | author=Barnett T, Goebel SJ, Nothdurft MA, Elting JJ |title=Carcinoembryonic antigen family: characterization of cDNAs coding for NCA and CEA and suggestion of nonrandom sequence variation in their conserved loop-domains. |journal=Genomics |volume=3 |issue= 1 |pages= 59–66 |year= 1989 |pmid= 3220478 |doi=
*cite journal | author=Zimmermann W, Weber B, Ortlieb B, "et al." |title=Chromosomal localization of the carcinoembryonic antigen gene family and differential expression in various tumors. |journal=Cancer Res. |volume=48 |issue= 9 |pages= 2550–4 |year= 1988 |pmid= 3356015 |doi=
*cite journal | author=Beauchemin N, Benchimol S, Cournoyer D, "et al." |title=Isolation and characterization of full-length functional cDNA clones for human carcinoembryonic antigen. |journal=Mol. Cell. Biol. |volume=7 |issue= 9 |pages= 3221–30 |year= 1987 |pmid= 3670312 |doi=
*cite journal | author=Oikawa S, Nakazato H, Kosaki G |title=Primary structure of human carcinoembryonic antigen (CEA) deduced from cDNA sequence. |journal=Biochem. Biophys. Res. Commun. |volume=142 |issue= 2 |pages= 511–8 |year= 1987 |pmid= 3814146 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Hart SP, Ross JA, Ross K, "et al." |title=Molecular characterization of the surface of apoptotic neutrophils: implications for functional downregulation and recognition by phagocytes. |journal=Cell Death Differ. |volume=7 |issue= 5 |pages= 493–503 |year= 2000 |pmid= 10800083 |doi= 10.1038/sj.cdd.4400680
*cite journal | author=Guignot J, Peiffer I, Bernet-Camard MF, "et al." |title=Recruitment of CD55 and CD66e brush border-associated glycosylphosphatidylinositol-anchored proteins by members of the Afa/Dr diffusely adhering family of Escherichia coli that infect the human polarized intestinal Caco-2/TC7 cells. |journal=Infect. Immun. |volume=68 |issue= 6 |pages= 3554–63 |year= 2000 |pmid= 10816511 |doi=
*cite journal | author=Boehm MK, Perkins SJ |title=Structural models for carcinoembryonic antigen and its complex with the single-chain Fv antibody molecule MFE23. |journal=FEBS Lett. |volume=475 |issue= 1 |pages= 11–6 |year= 2000 |pmid= 10854848 |doi=
*cite journal | author=Screaton RA, DeMarte L, Dráber P, Stanners CP |title=The specificity for the differentiation blocking activity of carcinoembryonic antigen resides in its glycophosphatidyl-inositol anchor. |journal=J. Cell Biol. |volume=150 |issue= 3 |pages= 613–26 |year= 2000 |pmid= 10931872 |doi=
*cite journal | author=Bajenova OV, Zimmer R, Stolper E, "et al." |title=Heterogeneous RNA-binding protein M4 is a receptor for carcinoembryonic antigen in Kupffer cells. |journal=J. Biol. Chem. |volume=276 |issue= 33 |pages= 31067–73 |year= 2001 |pmid= 11406629 |doi= 10.1074/jbc.M104093200
*cite journal | author=Wirth T, Soeth E, Czubayko F, Juhl H |title=Inhibition of endogenous carcinoembryonic antigen (CEA) increases the apoptotic rate of colon cancer cells and inhibits metastatic tumor growth. |journal=Clin. Exp. Metastasis |volume=19 |issue= 2 |pages= 155–60 |year= 2002 |pmid= 11964079 |doi=
*cite journal | author=Louhimo J, Carpelan-Holmström M, Alfthan H, "et al." |title=Serum HCG beta, CA 72-4 and CEA are independent prognostic factors in colorectal cancer. |journal=Int. J. Cancer |volume=101 |issue= 6 |pages= 545–8 |year= 2002 |pmid= 12237895 |doi= 10.1002/ijc.90009
*cite journal | author=Hampton R, Walker M, Marshall J, Juhl H |title=Differential expression of carcinoembryonic antigen (CEA) splice variants in whole blood of colon cancer patients and healthy volunteers: implication for the detection of circulating colon cancer cells. |journal=Oncogene |volume=21 |issue= 51 |pages= 7817–23 |year= 2002 |pmid= 12420218 |doi= 10.1038/sj.onc.1205906
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899

External links

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  • Carcinoembryonic antigen — (CEA) is a glycoprotein involved in cell adhesion. It is normally produced during fetal development, but the production of CEA stops before birth. Therefore, it is not usually present in the blood of healthy adults, although levels are raised in… …   Wikipedia

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