RHOBTB1

Rho-related BTB domain containing 1, also known as RHOBTB1, is a human gene.cite web | title = Entrez Gene: RHOBTB1 Rho-related BTB domain containing 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9886| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate transcriptional splice variants have been characterized.cite web | title = Entrez Gene: RHOBTB1 Rho-related BTB domain containing 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9886| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Nagase T, Ishikawa K, Suyama M, "et al." |title=Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=5 |issue= 5 |pages= 277–86 |year= 1999 |pmid= 9872452 |doi=
*cite journal | author=Rivero F, Dislich H, Glöckner G, Noegel AA |title=The Dictyostelium discoideum family of Rho-related proteins. |journal=Nucleic Acids Res. |volume=29 |issue= 5 |pages= 1068–79 |year= 2001 |pmid= 11222756 |doi=
*cite journal | author=Ramos S, Khademi F, Somesh BP, Rivero F |title=Genomic organization and expression profile of the small GTPases of the RhoBTB family in human and mouse. |journal=Gene |volume=298 |issue= 2 |pages= 147–57 |year= 2003 |pmid= 12426103 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Aspenström P, Fransson A, Saras J |title=Rho GTPases have diverse effects on the organization of the actin filament system. |journal=Biochem. J. |volume=377 |issue= Pt 2 |pages= 327–37 |year= 2004 |pmid= 14521508 |doi= 10.1042/BJ20031041
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Brandenberger R, Wei H, Zhang S, "et al." |title=Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. |journal=Nat. Biotechnol. |volume=22 |issue= 6 |pages= 707–16 |year= 2005 |pmid= 15146197 |doi= 10.1038/nbt971
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Beder LB, Gunduz M, Ouchida M, "et al." |title=Identification of a candidate tumor suppressor gene RHOBTB1 located at a novel allelic loss region 10q21 in head and neck cancer. |journal=J. Cancer Res. Clin. Oncol. |volume=132 |issue= 1 |pages= 19–27 |year= 2006 |pmid= 16170569 |doi= 10.1007/s00432-005-0033-0

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