ECEL1

Endothelin converting enzyme-like 1, also known as ECEL1, is a human gene.cite web | title = Entrez Gene: ECEL1 endothelin converting enzyme-like 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9427| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of the neutral endopeptidase (NEP)-related family. It is expressed specifically in the nervous system. The gene disruption in mouse embryonic stem cells results in neonatal lethality due to respiratory failure shortly after birth. Based on the specific expression of this gene and the phenotype of the gene deficiency in mouse embryos, it is suggested that the protein encoded by this gene play a critical role in the nervous regulation of the respiratory system.cite web | title = Entrez Gene: ECEL1 endothelin converting enzyme-like 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9427| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Valdenaire O, Richards JG, Faull RL, Schweizer A |title=XCE, a new member of the endothelin-converting enzyme and neutral endopeptidase family, is preferentially expressed in the CNS. |journal=Brain Res. Mol. Brain Res. |volume=64 |issue= 2 |pages= 211–21 |year= 1999 |pmid= 9931490 |doi=
*cite journal | author=Valdenaire O, Rohrbacher E, Langeveld A, "et al." |title=Organization and chromosomal localization of the human ECEL1 (XCE) gene encoding a zinc metallopeptidase involved in the nervous control of respiration. |journal=Biochem. J. |volume=346 Pt 3 |issue= |pages= 611–6 |year= 2000 |pmid= 10698686 |doi=
*cite journal | author=Rump A, Kasper G, Hayes C, "et al." |title=Complex arrangement of genes within a 220-kb region of double-duplicated DNA on human 2q37.1. |journal=Genomics |volume=73 |issue= 1 |pages= 50–5 |year= 2001 |pmid= 11352565 |doi= 10.1006/geno.2000.6504
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Kawamoto T, Ohira M, Hamano S, "et al." |title=High expression of the novel endothelin-converting enzyme genes, Nbla03145/ECEL1alpha and beta, is associated with favorable prognosis in human neuroblastomas. |journal=Int. J. Oncol. |volume=22 |issue= 4 |pages= 815–22 |year= 2003 |pmid= 12632073 |doi=
*cite journal | author=Clark HF, Gurney AL, Abaya E, "et al." |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003
*cite journal | author=Benoit A, Vargas MA, Desgroseillers L, Boileau G |title=Endothelin-converting enzyme-like 1 (ECEL1) is present both in the plasma membrane and in the endoplasmic reticulum. |journal=Biochem. J. |volume=380 |issue= Pt 3 |pages= 881–8 |year= 2004 |pmid= 14992683 |doi= 10.1042/BJ20040215
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Hillier LW, Graves TA, Fulton RS, "et al." |title=Generation and annotation of the DNA sequences of human chromosomes 2 and 4. |journal=Nature |volume=434 |issue= 7034 |pages= 724–31 |year= 2005 |pmid= 15815621 |doi= 10.1038/nature03466

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