PNPLA3

PNPLA3

Patatin-like phospholipase domain containing 3, also known as PNPLA3, is a human gene.cite web | title = Entrez Gene: PNPLA3 patatin-like phospholipase domain containing 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=80339| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. The encoded protein, which appears to be membrane bound, may be involved in the balance of energy usage/storage in adipocytes.cite web | title = Entrez Gene: PNPLA3 patatin-like phospholipase domain containing 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=80339| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Dunham I, Shimizu N, Roe BA, "et al." |title=The DNA sequence of human chromosome 22. |journal=Nature |volume=402 |issue= 6761 |pages= 489–95 |year= 1999 |pmid= 10591208 |doi= 10.1038/990031
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Collins JE, Goward ME, Cole CG, "et al." |title=Reevaluating human gene annotation: a second-generation analysis of chromosome 22. |journal=Genome Res. |volume=13 |issue= 1 |pages= 27–36 |year= 2003 |pmid= 12529303 |doi= 10.1101/gr.695703
*cite journal | author=Liu YM, Moldes M, Bastard JP, "et al." |title=Adiponutrin: A new gene regulated by energy balance in human adipose tissue. |journal=J. Clin. Endocrinol. Metab. |volume=89 |issue= 6 |pages= 2684–9 |year= 2004 |pmid= 15181042 |doi= 10.1210/jc.2003-031978
*cite journal | author=Jenkins CM, Mancuso DJ, Yan W, "et al." |title=Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities. |journal=J. Biol. Chem. |volume=279 |issue= 47 |pages= 48968–75 |year= 2005 |pmid= 15364929 |doi= 10.1074/jbc.M407841200
*cite journal | author=Collins JE, Wright CL, Edwards CA, "et al." |title=A genome annotation-driven approach to cloning the human ORFeome. |journal=Genome Biol. |volume=5 |issue= 10 |pages= R84 |year= 2005 |pmid= 15461802 |doi= 10.1186/gb-2004-5-10-r84
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Lake AC, Sun Y, Li JL, "et al." |title=Expression, regulation, and triglyceride hydrolase activity of Adiponutrin family members. |journal=J. Lipid Res. |volume=46 |issue= 11 |pages= 2477–87 |year= 2006 |pmid= 16150821 |doi= 10.1194/jlr.M500290-JLR200
*cite journal | author=Wilson PA, Gardner SD, Lambie NM, "et al." |title=Characterization of the human patatin-like phospholipase family. |journal=J. Lipid Res. |volume=47 |issue= 9 |pages= 1940–9 |year= 2006 |pmid= 16799181 |doi= 10.1194/jlr.M600185-JLR200

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