TNS1

Tensin 1, also known as TNS1, is a human gene.cite web | title = Entrez Gene: TNS1 tensin 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7145| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. A second transcript from this gene has been described, but its full length nature has not been determined.cite web | title = Entrez Gene: TNS1 tensin 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7145| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Jankowski SA, Gumucio DL |title=Genes for tensin, villin and desmin are linked on mouse chromosome 1. |journal=Mamm. Genome |volume=6 |issue= 10 |pages= 744–5 |year= 1996 |pmid= 8563175 |doi=
*cite journal | author=Salgia R, Pisick E, Sattler M, "et al." |title=p130CAS forms a signaling complex with the adapter protein CRKL in hematopoietic cells transformed by the BCR/ABL oncogene. |journal=J. Biol. Chem. |volume=271 |issue= 41 |pages= 25198–203 |year= 1996 |pmid= 8810278 |doi=
*cite journal | author=Dias Neto E, Correa RG, Verjovski-Almeida S, "et al." |title=Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 7 |pages= 3491–6 |year= 2000 |pmid= 10737800 |doi=
*cite journal | author=Katz BZ, Zohar M, Teramoto H, "et al." |title=Tensin can induce JNK and p38 activation. |journal=Biochem. Biophys. Res. Commun. |volume=272 |issue= 3 |pages= 717–20 |year= 2000 |pmid= 10860821 |doi= 10.1006/bbrc.2000.2853
*cite journal | author=Chen H, Ishii A, Wong WK, "et al." |title=Molecular characterization of human tensin. |journal=Biochem. J. |volume=351 Pt 2 |issue= |pages= 403–11 |year= 2001 |pmid= 11023826 |doi=
*cite journal | author=Benzing T, Gerke P, Höpker K, "et al." |title=Nephrocystin interacts with Pyk2, p130(Cas), and tensin and triggers phosphorylation of Pyk2. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 17 |pages= 9784–9 |year= 2001 |pmid= 11493697 |doi= 10.1073/pnas.171269898
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Yamashita M, Horikoshi S, Asanuma K, "et al." |title=Tensin is potentially involved in extracellular matrix production in mesangial cells. |journal=Histochem. Cell Biol. |volume=121 |issue= 3 |pages= 245–54 |year= 2004 |pmid= 14991332 |doi= 10.1007/s00418-004-0626-8
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026
*cite journal | author=Eto M, Kirkbride J, Elliott E, "et al." |title=Association of the tensin N-terminal protein-tyrosine phosphatase domain with the alpha isoform of protein phosphatase-1 in focal adhesions. |journal=J. Biol. Chem. |volume=282 |issue= 24 |pages= 17806–15 |year= 2007 |pmid= 17435217 |doi= 10.1074/jbc.M700944200

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