VPS33A

VPS33A

Vacuolar protein sorting 33 homolog A (S. cerevisiae), also known as VPS33A, is a human gene.cite web | title = Entrez Gene: VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=65082| accessdate = ]

PBB_Summary
section_title =
summary_text = Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and it encodes a protein similar to the yeast class C Vps33 protein. The mammalian class C VPS proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway.cite web | title = Entrez Gene: VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=65082| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Pevsner J, Hsu SC, Hyde PS, Scheller RH |title=Mammalian homologues of yeast vacuolar protein sorting (vps) genes implicated in Golgi-to-lysosome trafficking. |journal=Gene |volume=183 |issue= 1-2 |pages= 7–14 |year= 1997 |pmid= 8996080 |doi=
*cite journal | author=Huizing M, Didier A, Walenta J, "et al." |title=Molecular cloning and characterization of human VPS18, VPS 11, VPS16, and VPS33. |journal=Gene |volume=264 |issue= 2 |pages= 241–7 |year= 2001 |pmid= 11250079 |doi=
*cite journal | author=Kim BY, Krämer H, Yamamoto A, "et al." |title=Molecular characterization of mammalian homologues of class C Vps proteins that interact with syntaxin-7. |journal=J. Biol. Chem. |volume=276 |issue= 31 |pages= 29393–402 |year= 2001 |pmid= 11382755 |doi= 10.1074/jbc.M101778200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Suzuki T, Oiso N, Gautam R, "et al." |title=The mouse organellar biogenesis mutant buff results from a mutation in Vps33a, a homologue of yeast vps33 and Drosophila carnation. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 3 |pages= 1146–50 |year= 2003 |pmid= 12538872 |doi= 10.1073/pnas.0237292100
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Suzuki Y, Yamashita R, Shirota M, "et al." |title=Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. |journal=Genome Res. |volume=14 |issue= 9 |pages= 1711–8 |year= 2004 |pmid= 15342556 |doi= 10.1101/gr.2435604
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Gissen P, Johnson CA, Gentle D, "et al." |title=Comparative evolutionary analysis of VPS33 homologues: genetic and functional insights. |journal=Hum. Mol. Genet. |volume=14 |issue= 10 |pages= 1261–70 |year= 2005 |pmid= 15790593 |doi= 10.1093/hmg/ddi137

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