- BCL9
B-cell CLL/lymphoma 9, also known as BCL9, is a human
gene .cite web | title = Entrez Gene: BCL9 B-cell CLL/lymphoma 9| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=607| accessdate = ]PBB_Summary
section_title =
summary_text = BCL9 is associated with B-cell acute lymphoblastic leukemia. It may be a target of translocation in B-cell malignancies with abnormalities of 1q21. Its function is unknown. The overexpression of BCL9 may be of pathogenic significance in B-cell malignancies.cite web | title = Entrez Gene: BCL9 B-cell CLL/lymphoma 9| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=607| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Willis TG, Zalcberg IR, Coignet LJ, "et al." |title=Molecular cloning of translocation t(1;14)(q21;q32) defines a novel gene (BCL9) at chromosome 1q21. |journal=Blood |volume=91 |issue= 6 |pages= 1873–81 |year= 1998 |pmid= 9490669 |doi=
*cite journal | author=Busson-Le Coniat M, Salomon-Nguyen F, Dastugue N, "et al." |title=Fluorescence in situ hybridization analysis of chromosome 1 abnormalities in hematopoietic disorders: rearrangements of DNA satellite II and new recurrent translocations. |journal=Leukemia |volume=13 |issue= 12 |pages= 1975–81 |year= 2000 |pmid= 10602418 |doi=
*cite journal | author=Kramps T, Peter O, Brunner E, "et al." |title=Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex. |journal=Cell |volume=109 |issue= 1 |pages= 47–60 |year= 2002 |pmid= 11955446 |doi=
*cite journal | author=Knoll A, Dvorák J, Rohrer GA, Cepica S |title=Linkage and cytogenetic mapping of the BCL9 gene to porcine chromosome 4. |journal=Anim. Genet. |volume=33 |issue= 2 |pages= 162–3 |year= 2002 |pmid= 12047235 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Townsley FM, Thompson B, Bienz M |title=Pygopus residues required for its binding to Legless are critical for transcription and development. |journal=J. Biol. Chem. |volume=279 |issue= 7 |pages= 5177–83 |year= 2004 |pmid= 14612447 |doi= 10.1074/jbc.M309722200
*cite journal | author=Hoffmans R, Basler K |title=Identification and in vivo role of the Armadillo-Legless interaction. |journal=Development |volume=131 |issue= 17 |pages= 4393–400 |year= 2004 |pmid= 15294866 |doi= 10.1242/dev.01296
*cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, "et al." |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101
*cite journal | author=Sampietro J, Dahlberg CL, Cho US, "et al." |title=Crystal structure of a beta-catenin/BCL9/Tcf4 complex. |journal=Mol. Cell |volume=24 |issue= 2 |pages= 293–300 |year= 2006 |pmid= 17052462 |doi= 10.1016/j.molcel.2006.09.001
*cite journal | author=Hoffmans R, Basler K |title=BCL9-2 binds Arm/beta-catenin in a Tyr142-independent manner and requires Pygopus for its function in Wg/Wnt signaling. |journal=Mech. Dev. |volume=124 |issue= 1 |pages= 59–67 |year= 2007 |pmid= 17113272 |doi= 10.1016/j.mod.2006.09.006PBB_Controls
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