MAGEA12

Melanoma antigen family A, 12, also known as MAGEA12, is a human gene.cite web | title = Entrez Gene: MAGEA12 melanoma antigen family A, 12| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4111| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.cite web | title = Entrez Gene: MAGEA12 melanoma antigen family A, 12| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4111| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=De Plaen E, Arden K, Traversari C, "et al." |title=Structure, chromosomal localization, and expression of 12 genes of the MAGE family. |journal=Immunogenetics |volume=40 |issue= 5 |pages= 360–9 |year= 1994 |pmid= 7927540 |doi=
*cite journal | author=Ding M, Beck RJ, Keller CJ, Fenton RG |title=Cloning and analysis of MAGE-1-related genes. |journal=Biochem. Biophys. Res. Commun. |volume=202 |issue= 1 |pages= 549–55 |year= 1994 |pmid= 8037761 |doi= 10.1006/bbrc.1994.1963
*cite journal | author=De Smet C, Lurquin C, van der Bruggen P, "et al." |title=Sequence and expression pattern of the human MAGE2 gene. |journal=Immunogenetics |volume=39 |issue= 2 |pages= 121–9 |year= 1994 |pmid= 8276455 |doi=
*cite journal | author=Rogner UC, Wilke K, Steck E, "et al." |title=The melanoma antigen gene (MAGE) family is clustered in the chromosomal band Xq28. |journal=Genomics |volume=29 |issue= 3 |pages= 725–31 |year= 1996 |pmid= 8575766 |doi= 10.1006/geno.1995.9945
*cite journal | author=Mallon AM, Platzer M, Bate R, "et al." |title=Comparative genome sequence analysis of the Bpa/Str region in mouse and Man. |journal=Genome Res. |volume=10 |issue= 6 |pages= 758–75 |year= 2000 |pmid= 10854409 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Wischnewski F, Friese O, Pantel K, Schwarzenbach H |title=Methyl-CpG binding domain proteins and their involvement in the regulation of the MAGE-A1, MAGE-A2, MAGE-A3, and MAGE-A12 gene promoters. |journal=Mol. Cancer Res. |volume=5 |issue= 7 |pages= 749–59 |year= 2007 |pmid= 17634428 |doi= 10.1158/1541-7786.MCR-06-0364

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