- LGALS4
Lectin, galactoside-binding, soluble, 4 (galectin 4), also known as LGALS4, is a human
gene .cite web | title = Entrez Gene: LGALS4 lectin, galactoside-binding, soluble, 4 (galectin 4)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3960| accessdate = ]PBB_Summary
section_title =
summary_text = The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS4 is an S-type lectin that is strongly underexpressed in colorectal cancer. The 323-amino acid LGALS4 protein contains 2 homologous, approximately 150-amino acid carbohydrate recognition domains and all amino acids typically conserved in galectins.cite web | title = Entrez Gene: LGALS4 lectin, galactoside-binding, soluble, 4 (galectin 4)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3960| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Barondes SH, Cooper DN, Gitt MA, Leffler H |title=Galectins. Structure and function of a large family of animal lectins. |journal=J. Biol. Chem. |volume=269 |issue= 33 |pages= 20807–10 |year= 1994 |pmid= 8063692 |doi=
*cite journal | author=Huflejt ME, Jordan ET, Gitt MA, "et al." |title=Strikingly different localization of galectin-3 and galectin-4 in human colon adenocarcinoma T84 cells. Galectin-4 is localized at sites of cell adhesion. |journal=J. Biol. Chem. |volume=272 |issue= 22 |pages= 14294–303 |year= 1997 |pmid= 9162064 |doi=
*cite journal | author=Rechreche H, Mallo GV, Montalto G, "et al." |title=Cloning and expression of the mRNA of human galectin-4, an S-type lectin down-regulated in colorectal cancer. |journal=Eur. J. Biochem. |volume=248 |issue= 1 |pages= 225–30 |year= 1997 |pmid= 9310382 |doi=
*cite journal | author=Ideo H, Seko A, Ohkura T, "et al." |title=High-affinity binding of recombinant human galectin-4 to SO(3)(-)-->3Galbeta1-->3GalNAc pyranoside. |journal=Glycobiology |volume=12 |issue= 3 |pages= 199–208 |year= 2002 |pmid= 11971864 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Ideo H, Seko A, Yamashita K |title=Galectin-4 binds to sulfated glycosphingolipids and carcinoembryonic antigen in patches on the cell surface of human colon adenocarcinoma cells. |journal=J. Biol. Chem. |volume=280 |issue= 6 |pages= 4730–7 |year= 2005 |pmid= 15546874 |doi= 10.1074/jbc.M410362200
*cite journal | author=Delacour D, Gouyer V, Zanetta JP, "et al." |title=Galectin-4 and sulfatides in apical membrane trafficking in enterocyte-like cells. |journal=J. Cell Biol. |volume=169 |issue= 3 |pages= 491–501 |year= 2005 |pmid= 15883199 |doi= 10.1083/jcb.200407073
*cite journal | author=Stowell SR, Karmakar S, Stowell CJ, "et al." |title=Human galectin-1, -2, and -4 induce surface exposure of phosphatidylserine in activated human neutrophils but not in activated T cells. |journal=Blood |volume=109 |issue= 1 |pages= 219–27 |year= 2007 |pmid= 16940423 |doi= 10.1182/blood-2006-03-007153
*cite journal | author=Ideo H, Seko A, Yamashita K |title=Recognition mechanism of galectin-4 for cholesterol 3-sulfate. |journal=J. Biol. Chem. |volume=282 |issue= 29 |pages= 21081–9 |year= 2007 |pmid= 17545668 |doi= 10.1074/jbc.M703770200PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes
Wikimedia Foundation. 2010.