VPREB3

Pre-B lymphocyte gene 3, also known as VPREB3, is a human gene.cite web | title = Entrez Gene: VPREB3 pre-B lymphocyte gene 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=29802| accessdate = ]

PBB_Summary
section_title =
summary_text = The VPREB3 gene product is the human homologue of the mouse VpreB3 (8HS20) protein, and is specifically expressed in cell lines representative of all stages of B-cell differentiation. It is also related to VPREB1 and other members of the immunoglobulin supergene family. The VPREB3 protein associates with membrane mu heavy chains early in the course of pre-B cell receptor biosynthesis. The precise function of VPREB3 is not known, but it may contribute to mu chain transport in pre-B cells.cite web | title = Entrez Gene: VPREB3 pre-B lymphocyte gene 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=29802| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Melchers F, Karasuyama H, Haasner D, "et al." |title=The surrogate light chain in B-cell development. |journal=Immunol. Today |volume=14 |issue= 2 |pages= 60–8 |year= 1993 |pmid= 8166770 |doi=
*cite journal | author=Ohnishi K, Takemori T |title=Molecular components and assembly of mu.surrogate light chain complexes in pre-B cell lines. |journal=J. Biol. Chem. |volume=269 |issue= 45 |pages= 28347–53 |year= 1994 |pmid= 7961773 |doi=
*cite journal | author=Rosnet O, Mattéi MG, Delattre O, Schiff C |title=VPREB3: cDNA characterization and expression in human and chromosome mapping in human and mouse. |journal=Cytogenet. Cell Genet. |volume=87 |issue= 3-4 |pages= 205–8 |year= 2000 |pmid= 10702669 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Clark HF, Gurney AL, Abaya E, "et al." |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003
*cite journal | author=Rosnet O, Blanco-Betancourt C, Grivel K, "et al." |title=Binding of free immunoglobulin light chains to VpreB3 inhibits their maturation and secretion in chicken B cells. |journal=J. Biol. Chem. |volume=279 |issue= 11 |pages= 10228–36 |year= 2004 |pmid= 14670953 |doi= 10.1074/jbc.M312169-A200
*cite journal | author=Collins JE, Wright CL, Edwards CA, "et al." |title=A genome annotation-driven approach to cloning the human ORFeome. |journal=Genome Biol. |volume=5 |issue= 10 |pages= R84 |year= 2005 |pmid= 15461802 |doi= 10.1186/gb-2004-5-10-r84
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rangel R, McKeller MR, Sims-Mourtada JC, "et al." |title=Assembly of the kappa preB receptor requires a V kappa-like protein encoded by a germline transcript. |journal=J. Biol. Chem. |volume=280 |issue= 18 |pages= 17807–14 |year= 2005 |pmid= 15757909 |doi= 10.1074/jbc.M409479200

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