ELP4

Elongation protein 4 homolog (S. cerevisiae), also known as ELP4, is a human gene.cite web | title = Entrez Gene: ELP4 elongation protein 4 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26610| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a component of the six subunit elongator complex, a histone acetyltransferase complex that associates directly with RNA polymerase II during transcriptional elongation. The human gene can partially complement sensitivity phenotypes of yeast ELP4 deletion mutants. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.cite web | title = Entrez Gene: ELP4 elongation protein 4 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26610| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=
*cite journal | author=Wiemann S, Weil B, Wellenreuther R, "et al." |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701
*cite journal | author=Winkler GS, Petrakis TG, Ethelberg S, "et al." |title=RNA polymerase II elongator holoenzyme is composed of two discrete subcomplexes. |journal=J. Biol. Chem. |volume=276 |issue= 35 |pages= 32743–9 |year= 2001 |pmid= 11435442 |doi= 10.1074/jbc.M105303200
*cite journal | author=Hawkes NA, Otero G, Winkler GS, "et al." |title=Purification and characterization of the human elongator complex. |journal=J. Biol. Chem. |volume=277 |issue= 4 |pages= 3047–52 |year= 2002 |pmid= 11714725 |doi= 10.1074/jbc.M110445200
*cite journal | author=Kim JH, Lane WS, Reinberg D |title=Human Elongator facilitates RNA polymerase II transcription through chromatin. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 3 |pages= 1241–6 |year= 2002 |pmid= 11818576 |doi= 10.1073/pnas.251672198
*cite journal | author=Kleinjan DA, Seawright A, Elgar G, van Heyningen V |title=Characterization of a novel gene adjacent to PAX6, revealing synteny conservation with functional significance. |journal=Mamm. Genome |volume=13 |issue= 2 |pages= 102–7 |year= 2002 |pmid= 11889558 |doi= 10.1007/s00335-001-3058-y
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Li F, Han QJ, Luo DH, "et al." |title= [The Elp4 subunit of human Elongator complex partially complements the growth defects of yeast ELP4 deletion strain] |journal=Yi Chuan Xue Bao |volume=31 |issue= 7 |pages= 668–74 |year= 2004 |pmid= 15473317 |doi=
*cite journal | author=Wiemann S, Arlt D, Huber W, "et al." |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136–44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704
*cite journal | author=Mehrle A, Rosenfelder H, Schupp I, "et al." |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415–8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139

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