APPBP2

Amyloid beta precursor protein (cytoplasmic tail) binding protein 2, also known as APPBP2, is a human gene.cite web | title = Entrez Gene: APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10513| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene.cite web | title = Entrez Gene: APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10513| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Nagase T, Seki N, Ishikawa K, "et al." |title=Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. |journal=DNA Res. |volume=3 |issue= 5 |pages= 321–9, 341–54 |year= 1997 |pmid= 9039502 |doi=
*cite journal | author=Zheng P, Eastman J, Vande Pol S, Pimplikar SW |title=PAT1, a microtubule-interacting protein, recognizes the basolateral sorting signal of amyloid precursor protein. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 25 |pages= 14745–50 |year= 1999 |pmid= 9843960 |doi=
*cite journal | author=Bärlund M, Monni O, Kononen J, "et al." |title=Multiple genes at 17q23 undergo amplification and overexpression in breast cancer. |journal=Cancer Res. |volume=60 |issue= 19 |pages= 5340–4 |year= 2000 |pmid= 11034067 |doi=
*cite journal | author=Monni O, Barlund M, Mousses S, "et al." |title=Comprehensive copy number and gene expression profiling of the 17q23 amplicon in human breast cancer. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 10 |pages= 5711–6 |year= 2001 |pmid= 11331760 |doi= 10.1073/pnas.091582298
*cite journal | author=Gao Y, Pimplikar SW |title=The gamma -secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 26 |pages= 14979–84 |year= 2002 |pmid= 11742091 |doi= 10.1073/pnas.261463298
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Benboudjema L, Mulvey M, Gao Y, "et al." |title=Association of the herpes simplex virus type 1 Us11 gene product with the cellular kinesin light-chain-related protein PAT1 results in the redistribution of both polypeptides. |journal=J. Virol. |volume=77 |issue= 17 |pages= 9192–203 |year= 2003 |pmid= 12915535 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209

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