BAG5

BCL2-associated athanogene 5, also known as BAG5, is a human gene.cite web | title = Entrez Gene: BAG5 BCL2-associated athanogene 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9529| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene.cite web | title = Entrez Gene: BAG5 BCL2-associated athanogene 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9529| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Takayama S, Sato T, Krajewski S, "et al." |title=Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity. |journal=Cell |volume=80 |issue= 2 |pages= 279–84 |year= 1995 |pmid= 7834747 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Höhfeld J, Jentsch S |title=GrpE-like regulation of the hsc70 chaperone by the anti-apoptotic protein BAG-1. |journal=EMBO J. |volume=16 |issue= 20 |pages= 6209–16 |year= 1997 |pmid= 9321400 |doi= 10.1093/emboj/16.20.6209
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Takayama S, Xie Z, Reed JC |title=An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators. |journal=J. Biol. Chem. |volume=274 |issue= 2 |pages= 781–6 |year= 1999 |pmid= 9873016 |doi=
*cite journal | author=Nagase T, Ishikawa K, Suyama M, "et al." |title=Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=5 |issue= 6 |pages= 355–64 |year= 1999 |pmid= 10048485 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Kalia SK, Lee S, Smith PD, "et al." |title=BAG5 inhibits parkin and enhances dopaminergic neuron degeneration. |journal=Neuron |volume=44 |issue= 6 |pages= 931–45 |year= 2005 |pmid= 15603737 |doi= 10.1016/j.neuron.2004.11.026

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